新型冠状病毒肺炎对心血管系统影响

doi:10.3969/j.issn.1006-7795.2020.04.028

首都医科大学学报 ›› 2020, Vol. 41 ›› Issue (4): 657-663.doi: 10.3969/j.issn.1006-7795.2020.04.028

新型冠状病毒肺炎对心血管系统影响

杨毅¹, 鲁旭然¹, 刘楠¹, 侯晓彤¹, 孙立忠², 吴龙³, 潘友民⁴, 王守凤¹, 赵欣艳¹

1. 首都医科大学附属北京安贞医院心外科危重症中心北京市心肺血管疾病研究所, 北京 100029;
2. 首都医科大学附属北京安贞医院心脏外科北京市心肺血管疾病研究所北京市大血管疾病诊疗研究中心, 北京 100029;
3. 华中科技大学同济医学院附属协和医院心脏大血管外科, 武汉 430022;
4. 华中科技大学同济医学院附属同济医院外科大血管外科, 武汉 430030

收稿日期:2020-03-14 出版日期:2020-08-21 发布日期:2020-07-22
通讯作者: 刘楠 E-mail:ln9102@vip.126.com
基金资助:
国家科技支撑计划项目（2015BAI12B03），北京市科技重大专项课题（Z171100001017083）。

Effects of COVID-19 on cardiovascular system

Yang Yi¹, Lu Xuran¹, Liu Nan¹, Hou Xiaotong¹, Sun Lizhong², Wu Long³, Pan Youmin⁴, Wang Shoufeng¹, Zhao Xinyan¹

1. Center for Cardiac Intensive Care, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing 100029, China;
2. Department of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, Aortic Disease Center of Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing 100029, China;
3. Department of Cardiovascular Surgery, Union Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology, Wuhan 430022, China;
4. Department of Cardiovascular Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science & Technology, Wuhan 430030, China

Received:2020-03-14 Online:2020-08-21 Published:2020-07-22
Supported by:
This study was supported by National Science and Technology Support Program of China(2015BAI12B03), Beijing Major Science and Technology Projects from Beijing Municipal Science and Technology Commission(Z171100001017083).

摘要/Abstract

摘要： 新型冠状病毒肺炎（COVID-19）除了典型呼吸系统症状，也有一定比例COVID-19患者出现了心血管系统受损的临床表现且此类患者进展为重症或死亡的概率较高。目前对于COVID-19的病理机制尚未完全了解，心血管系统的变化也有待进一步分析研究。本文综合目前已有文献，分析与初步探索心血管系统可能的损伤机制，包括病毒直接损伤心肌细胞及传导系统，合并症或伴随情况如低氧血症、炎性反应、应激等对心血管系统的损害以及药物的影响等。

关键词: 新型冠状病毒肺炎, 心血管系统, 多脏器衰竭

Abstract: In addition to typical respiratory system symptoms, some patients with COVID-19 have a clinical presentation of cardiovascular impairment. Such patients are more likely to progress to severe illness or death. However, the pathological mechanism of COVID-19 is not yet fully understood, and the changes of cardiovascular system need further analysis and research. Based on the existing literature, this paper preliminarily reviewed the possible damage mechanism of cardiovascular system, including the direct damage of myocardial cells and conduction system by virus, the damage of cardiovascular system by complications or accompanying conditions such as hypoxemia, inflammatory response, stress, and the influence of drugs.

Key words: COVID-19, cardiovascular system, multiple organ failure

中图分类号:

R563.1

杨毅, 鲁旭然, 刘楠, 侯晓彤, 孙立忠, 吴龙, 潘友民, 王守凤, 赵欣艳. 新型冠状病毒肺炎对心血管系统影响[J]. 首都医科大学学报, 2020, 41(4): 657-663.

Yang Yi, Lu Xuran, Liu Nan, Hou Xiaotong, Sun Lizhong, Wu Long, Pan Youmin, Wang Shoufeng, Zhao Xinyan. Effects of COVID-19 on cardiovascular system[J]. Journal of Capital Medical University, 2020, 41(4): 657-663.

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新型冠状病毒肺炎对心血管系统影响

Effects of COVID-19 on cardiovascular system

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