耳科影像学的关键技术创新和应用——2020年度国家科学技术进步奖二等奖

doi:10.3969/j.issn.1006-7795.2022.01.003

摘要/Abstract

摘要： 耳科疾病病变具有解剖位置深、隐匿微小的特征,传统耳科影像学在临床应用时存在看不清、看不准、看不懂的问题,导致病变影像诊断效能低下。王振常教授团队从创建耳科影像的规范检查方案和系统评价模式、提升耳科疾病的病理生理结构显示能力入手,阐明了搏动性耳鸣全链条发生机制,构建耳科影像检查及诊断新体系,并研制十微米级临床耳科电子计算机断层扫描(computed tomography, CT)专用设备,实现低辐射高质量的成像和病变的精准检查,显著提升了诊断效能。

关键词: 搏动性耳鸣, 耳聋, 眩晕, 体层摄影术,X 线计算机, 诊断

Abstract: The otologic diseases features in deep and occult anatomy. The problems of traditional oto-radiology with invisibility, imprecision, and incomprehensibility leads to diagnostic inefficacy. Professor Wang Zhenchang's team developed a canonical oto-radiological examination protocol and systemic evaluation model to improve the visibility of pathophysiological features of otology disease. They illuminated the whole chain mechanism of pulsatile tinnitus, established the radiological examination and evaluation system of oto-radiology, invented micron-level computed tomography specific to clinical otology. By applying this program, they could precisely detect the disease with low-dose as well as high-quality radiological examination. The diagnostic efficacy was improved significantly.

Key words: pulsatile tinnitus, deafness, vertigo, tomography, X-ray computed, diagnosis

中图分类号:

R816.96

吕晗, 赵鹏飞, 尹红霞, 王振常. 耳科影像学的关键技术创新和应用——2020年度国家科学技术进步奖二等奖[J]. 首都医科大学学报, 2022, 43(1): 13-16.

Lyu Han, Zhao Pengfei, Yin Hongxia, Wang Zhenchang. The innovation and application of key technologies in the otological radiology——The Second Prize of 2020 National Science and Technology Progress[J]. Journal of Capital Medical University, 2022, 43(1): 13-16.

参考文献

[1] Dong C, Zhao P F, Yang J G, et al. Incidence of vascular anomalies and variants associated with unilateral venous pulsatile tinnitus in 242 patients based on dual-phase contrast-enhanced computed tomography[J]. Chin Med J, 2015, 128(5): 581-585.
[2] Zhao P F, Lv H, Dong C, et al. CT evaluation of sigmoid plate dehiscence causing pulsatile tinnitus[J]. Eur Radiol, 2016, 26(1): 9-14.
[3] Liu Z, Bi W, Li J, et al. Superior semicircular canal dehiscence in relation to the superior petrosal sinus: a potential cause of pulsatile tinnitus[J]. Clin Radiol, 2015, 70(9): 943-947.
[4] Liu Z H, Li J, Zhao P F, et al. Sigmoid plate dehiscence: congenital or acquired condition?[J]. Eur J Radiol, 2015, 84(5): 862-864.
[5] Zhao P F, Wang Z C, Xian J F, et al. Persistent petrosquamosal sinus in adults: qualitative imaging evaluation on high-resolution CT venography[J]. Acta Radiol, 2014, 55(2): 225-230.
[6] Lv H, Zhao P F, Liu Z H, et al. Abnormal regional activity and functional connectivity in resting-state brain networks associated with etiology confirmed unilateral pulsatile tinnitus in the early stage of disease[J]. Hear Res, 2017, 346: 55-61.
[7] Lv H, Liu Z H, Yan F, et al. Abnormal baseline brain activity in patients with pulsatile tinnitus: a resting-state FMRI study[J]. Neural Plast, 2014, 2014: 549162.
[8] Niu Y T, Mehta D, Zhang Z R, et al. Radiation dose reduction in temporal bone CT with iterative reconstruction technique[J]. AJNR Am J Neuroradiol, 2012, 33(6): 1020-1026.
[9] Niu Y T, Olszewski M E, Zhang Y X, et al. Experimental study and optimization of scan parameters that influence radiation dose in temporal bone high-resolution multidetector row CT[J]. AJNR Am J Neuroradiol, 2011, 32(10): 1783-1788.
[10] Niu Y, Wang Z, Liu Y, et al. Radiation dose to the lens using different temporal bone CT scanning protocols[J]. AJNR Am J Neuroradiol, 2010, 31(2): 226-229.
[11] Zhang L C, Sha Y, Wang Z M, et al. 3D image of the middle ear ossicles: three protocols of post-processing based on multislice computed tomography[J]. Eur Arch Otorhinolaryngol, 2011, 268(5): 677-683.
[12] Wu Q R, Dai C F, Zhao M L, et al. The correlation between symptoms of definite Meniere's disease and endolymphatic hydrops visualized by magnetic resonance imaging[J]. Laryngoscope, 2016, 126(4): 974-979.
[13] Li L, Xing Y X, Chen Z Q, et al. A curve-filtered FDK (C-FDK) reconstruction algorithm for circular cone-beam CT[J]. J Xray Sci Technol, 2011, 19(3): 355-371.
[14] Wu D F, Xu X F, Zhang L, et al. A hybrid Monte Carlo model for the energy response functions of X-ray photon counting detectors[J]. Nucl Instrum Methods Phys Res A, 2016, 830: 397-406.
[15] Jin X, Li L, Chen Z Q, et al. Motion-compensated reconstruction method based on rigid motion model with multi-object[J]. Tsinghua Sci Technol, 2010, 15(1): 120-126.
[16] 中华医学会放射学分会头颈学组. 耳部CT和MRI检查及诊断专家共识[J]. 中华放射学杂志, 2017, 51(9): 654-659.
[17] 中华医学会放射学分会头颈学组. 搏动性耳鸣影像学检查方法与路径指南[J]. 中华医学杂志, 2013, 93(33): 2611-2612.
[18] Liu Z H, Chen C F, Wang Z C, et al. Sigmoid sinus diverticulum and pulsatile tinnitus: analysis of CT scans from 15 cases[J]. Acta Radiol, 2013, 54(7): 812-816.
[19] Lv H, Liu Z H, Yan F, et al. Disrupted neural activity in unilateral vascular pulsatile tinnitus patients in the early stage of disease: evidence from resting-state fMRI[J]. Prog Neuropsychopharmacol Biol Psychiatry, 2015, 59: 91-99.
[20] Expert Panel on Neurologic Imaging. ACR appropriateness criteria^© tinnitus[J]. J Am Coll Radiol, 2017, 14(11S): S584-S591.
[21] Liu F, Huang W N, Meng X X, et al. Comparison of noninvasive evaluation of endolymphatic hydrops in Meniere's disease and endolymphatic space in healthy volunteers using magnetic resonance imaging[J]. Acta Otolaryngol, 2012, 132(3): 234-240.
[22] Expert Panel on Neurologic Imaging. ACR appropriateness criteria^© hearing loss and/or vertigo[J]. J Am Coll Radiol, 2018, 15(11S): S321-S331.
[23] 牛延涛, 张永县, 康天良, 等. 成年人CT扫描中辐射剂量和诊断参考水平的探讨[J]. 中华放射医学与防护杂志, 2016, 36(11): 862-867.