首都医科大学学报 ›› 2021, Vol. 42 ›› Issue (6): 1046-1052.doi: 10.3969/j.issn.1006-7795.2021.06.023

• 临床研究 • 上一篇    下一篇

女性外阴巨大溃疡临床分析和经验总结

高广程1, 孙欣2, 许颖3, 禚风麟1*   

  1. 1.首都医科大学附属北京友谊医院皮肤性病科, 北京 100050;
    2.首都医科大学附属北京佑安医院皮肤性病科, 北京 100069;
    3.首都医科大学附属北京友谊医院临床检验中心, 北京 100050
  • 收稿日期:2021-05-11 出版日期:2021-12-21 发布日期:2021-12-17
  • 基金资助:
    病原微生物生物安全国家重点实验室开放基金(SKLPBS1830)。

Clinical analysis and experience summary of large vulvar ulcers in women

Gao Guangcheng1, Sun Xin2, Xu Ying3, Zhuo Fenglin1*   

  1. 1. Department of Dermatology,Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China;
    2. Department of Dermatology,Beijing Youan Hospital,Capital Medical University, Beijing 100069, China;
    3. Laboratory Center,Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China
  • Received:2021-05-11 Online:2021-12-21 Published:2021-12-17
  • Contact: * E-mail: zflsunny@hotmail.com
  • Supported by:
    Open Fund of State Key Laboratory for Biosafety of Pathogenic Microorganisms(SKLPBS1830).

摘要: 目的 探讨外阴巨大溃疡临床表现及诊断思路。方法 通过对3例外阴巨大溃疡患者的临床资料进行分析,并行文献检索,例举外阴巨大溃疡的种类和临床表现,进行诊断和鉴别诊断。结果 3例女性外阴巨大型溃疡,通过临床表现和实验室检查等分别确诊为白塞病、固定药疹和急性女性外阴溃疡,治疗后痊愈。结论 临床上遇到巨大女性外阴溃疡病例,需要考虑急性女性外阴溃疡、白塞综合征、固定型药疹、乳房外Paget’病、化学性烧伤和放射性溃疡。尤其是白塞病和急性女性外阴溃疡的诊断和鉴别诊断更为关键。具有口腔溃疡和外阴溃疡就可以诊断为白塞病。

关键词: 外阴巨大溃疡, 病例分析, 诊断和鉴别诊断, 白塞病

Abstract: Objective To explore the clinical manifestations and differential diagnosis of large vulvar ulcers. Methods By analyzing the clinical data of 3 patients with large vulvar ulcer and literature reports, the types and clinical manifestations of large vulvar ulcers were listed for diagnosis and differential diagnosis. Results Three cases of large vulvar ulcer were diagnosed as Behcet’s disease, fixed drug rash and acute vulvar ulcer, respectively, based on clinical manifestations and laboratory examinations. They were cured after treatments. Conclusion Acute vulvar ulcer, Behcet’s syndrome, fixed drug rash, extramammary Paget’s disease, chemical burn and radiation ulcer should be considered in the cases of large vulvar ulcers. Especially the diagnosis and differential diagnosis of Behcet’s disease and acute vulvar ulcer are more critical. Behcet’s disease can be diagnosed when patients have oral ulcer and vulvar ulcer.

Key words: massive ulceration of the vulva, case analysis, diagnosis and differential diagnosis, Behcet’s syndrome

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