Impact of administration route of tranexamic acid on pain and function of early and medium stage after arthroscopic rotator cuff repair

doi:10.3969/j.issn.1006-7795.2023.03.018

Abstract

Abstract: Objective To evaluate the impact of administration route of tranexamic acid on pain and function of early and medium stage after arthroscopic rotator cuff repair. Methods A retrospective analysis of clinical data of patients with rotator cuff tear in Beijing Chaoyang Hospital, Capital Medical University from January 2021 to December 2021. A total of 64 patients met the criteria, including 32 males and 32 females, aged 39－70 years. There were three administration routes of tranexamic acid, including intra-articular injection, intravenous drip and combined administration. Rotator cuff tear was repaired using double-row suture bridge technique. The Visual Analogue Scale （VAS） score and edema degree after surgery 1－3 d were analyzed. Function scores before surgery, 3 months and 6 months after surgery were analyzed. Shoulder range of motion before surgery, 3 d, 3 months and 6 months after surgery were analyzed. Results All patients were successfully operated, no serious complication occurred during or after surgery. Compared with intra-articular injection group and intravenous group, the combined administration group showed better VAS score and edema degree after surgery 1 d and 2 d (P<0.05). Also, a better range of motion 3 d postoperative, including forward flexion, abduction and external rotation, was found (P<0.05). No other significant differences were found. Conclusions Combined administration of tranexamic acid can improve pain, edema, range of motion and function of shoulder after surgery better than intra-articular injection or intravenous drip alone.

Key words: rotator cuff tear, tranexamic acid, arthroscopy, administration route

CLC Number:

R686

Yu Yang, Zhang Xiaogang, Lin Yuan, Ren Shixiang, Jia Jialin, Zhang Yuhan, Zhang Bo. Impact of administration route of tranexamic acid on pain and function of early and medium stage after arthroscopic rotator cuff repair[J]. Journal of Capital Medical University, 2023, 44(3): 475-481.

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URL: https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/10.3969/j.issn.1006-7795.2023.03.018

https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/Y2023/V44/I3/475

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