Journal of Capital Medical University ›› 2023, Vol. 44 ›› Issue (4): 511-516.doi: 10.3969/j.issn.1006-7795.2023.04.001

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Research progress of new radioactive tracers for cerebral glioma

Wang Kai, Yuan Leilei, Chen Qian, Ai Lin*   

  1. Department of Nuclear Medicine, Beijing Tiantan Hospital, Capital Medical University, Beijing  100070, China
  • Received:2023-06-02 Online:2023-08-21 Published:2023-07-23

Abstract: New positron emission tomography (PET) radiopharmaceuticals have potential clinical application value in the diagnosis and treatment of glioma patients. In addition to commonly used 18F-fluorodeoxyglucose and amino acid tracers, it is still necessary to develop new PET tracers for studying other biological characteristics of glioma, including perfusion, angiogenesis, hypoxia, neuroinflammation, cell proliferation, and tumor invasiveness. At present, these radioactive drugs are still being further explored and need to be validated through clinical trials to achieve their clinical conversion in the diagnosis, treatment, and evaluation of gliomas.

Key words: glioma, positron emission tomography (PET), radioactive tracer, 18F-fluorodeoxyglucose (18F-FDG), amino acid

CLC Number: