Novel drug therapies promote the treatment progress of primary central nervous system lymphoma

doi:10.3969/j.issn.1006-7795.2023.05.011

Abstract

Abstract: Primary central nervous system lymphoma is a rare and highly aggressive extranodal non-Hodgkin lymphoma. Up to date, there is no optimal treatment strategy. Currently, high-dose methotrexate-based chemotherapy serves as the first-line approach. Despite achieving some efficacy in disease control, its toxic side effects and limitations cannot be overlooked. With deeper molecular research in this disease, the significant breakthroughs in novel drug therapies like targeted treatment and immunotherapy have achieved. The exploration of combinations between different drug therapies has expanded the horizons of related treatments, propelling advancements in the treatment of primary central nervous system lymphoma.

Key words: primary central nervous system lymphoma, induction therapy, consolidation therapy, relapse/refractory, novel drug therapies

CLC Number:

R739.4

Yin Shuo, Chen Feng, Zheng Xiaohong, Zhang Weichunbai, Li Wenbin. Novel drug therapies promote the treatment progress of primary central nervous system lymphoma[J]. Journal of Capital Medical University, 2023, 44(5): 775-781.

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URL: https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/10.3969/j.issn.1006-7795.2023.05.011

https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/Y2023/V44/I5/775

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