Prediction of 14 day mortality in patients with hyperlactatemia septic shock by different lactate markers

doi:10.3969/j.issn.1006-7795.2018.01.003

Abstract

Abstract: Objective To explore which lactate marker (initial lactate value, lactate clearance and area under the lactate curve) is the best predictor of early mortality in patients with septic shock.Methods According to the prognosis, the patients were divided into nonsurvival and survival group, We compared with the difference between the predicted markers of lactate, and evaluated which kind of lactate marker was the best for early mortality in patients with septic shock.Results The receiver operating characteristic (ROC) curve showed that the area under curve(AUC) of the lactate and 24 h lactate could effectively predict the 14-day mortality. The predicted value was significantly higher than the initial lactate value and lactate clearance rate and the area under curve of the lactate (AUC=0.72,P=0.001).Conclusion Twenty-four hour lactate is the best predictor of 14-day mortality in patients with septic shock, and is superior to other lactate markers.

Key words: septic shock, lactate, area under curve, mortality

CLC Number:

Li Wen, Ren Shan, Jiang Li, Zhu Bo, Jiang Qi, Xi Xiuming. Prediction of 14 day mortality in patients with hyperlactatemia septic shock by different lactate markers[J]. Journal of Capital Medical University, 2018, 39(1): 9-13.

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URL: https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/10.3969/j.issn.1006-7795.2018.01.003

https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/Y2018/V39/I1/9

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