首都医科大学学报 ›› 2012, Vol. 33 ›› Issue (1): 94-98.doi: 10.3969/j.issn.1006-7795.2012.01.019

• 基础研究 • 上一篇    下一篇

基于隐结构法的寻常型银屑病常见证候要素的研究

徐雯洁1, 王天芳2, 刘卫红1, 吴秀艳2, 张会娜1, 张广中3, 张连文4, 姜春燕3, 陈维文3, 刘瓦利5, 瞿幸6, 王萍3, 李萍1   

  1. 1. 北京市中医研究所流调室, 北京 100010;2. 北京中医药大学中医诊断系, 北京 100029;3. 首都医科大学附属北京中医医院皮肤科, 北京 100010;4. 香港科技大学计算机系, 香港;5. 中国中医科学院广安门医院皮肤科, 北京 100053;6. 北京中医药大学东直门医院皮肤科, 北京 100700
  • 收稿日期:2011-08-31 修回日期:1900-01-01 出版日期:2012-02-21 发布日期:2012-02-21
  • 通讯作者: 王萍, 李萍

Research of the normal syndrome element of psoriasis vulgaris by latent structure theory

XU Wen-jie, WANG Tian-fang, LIU Wei-hong, WU Xiu-yan, ZHANG Hui-na, ZHANG Guang-zhong, ZHANG Lian-wen, JIANG Chun-yan, CHEN Wei-wen, LIU Wa-li, QU Xing, WANG Ping, LI Ping

  

  1. 1. Epidemiology Unit of Beijing Research Institute of Chinese Medicine, Beijing 100010;2. Diagnosis Department of Beijing University of Chinese Medicine, Beijing 100029, China;3. Department of, Dermatology Beijing Traditional Chinese Medicine Hospital, Capital Medical University, Beijing 100010, China;4. Department of Computer Science and Engineering, Hong Kong University of Science and Technology, Hong Kong, China;5. Department of Dermatology, Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China;6. Department of Dermatology, Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine, Beijing 100700, China
  • Received:2011-08-31 Revised:1900-01-01 Online:2012-02-21 Published:2012-02-21

摘要: 目的 运用隐结构法提取寻常型银屑病常见证候要素及其对应症状。方法 用统一制定的临床信息采集表收集寻常型银屑病患者的症状信息,建立数据库并进行数据的录入与预处理,用隐结构法分析数据,并结合中医专业知识对获得的隐结构模型进行诠释。结果 寻常型银屑病隐结构模型中共计有43个隐变量和111个隐类,经结合专业知识诠释,初步获取寻常型银屑病涉及的病位类证候要素为:血分、肝、肾、脾,病性类证候要素为:血热、血瘀、血虚、血燥、阳虚、气虚、阴虚、湿、火(热)。结论通过隐结构法分析寻常型银屑病的前瞻性无监督数据发现,隐结构法的模型构建与中医理论有相似之处,且比有监督的数据分析有更好的客观性。本研究为进一步建立寻常型银屑病的症候诊断标准提供了依据。

关键词: 隐结构法, 寻常型银屑病, 证候要素

Abstract: Objective To find out the normal syndrome elements and symptoms of psoriasis vulgaris by using latent structure theory. Methods The symptoms of psoriasis vulgaris patients were collected by a uniform form, psoriasis vulgaris database was established and the data were copied into the database. The data were analyzed by constructing a Psoriasis Vulgaris latent structure model, and the results were explained by professional knowledge of Chinese Medicine. Results The latent structure model of psoriasis vulgaris had 43 latent variables and 111 latent categories. By using the Chinese medicine theory, it was concluded that the syndrome-elements of location of psoriasis vulgaris were: blood, liver, kidney, and spleen; the syndrome-elements of nature of disease of psoriasis vulgaris were: heat of blood, blood stasis, blood deficiency, dry because of blood deficiency, yang deficiency, qi deficiency, yin deficiency, dampness and heat. Conclusion The research used latent structure to analyze the data by no supervising, found latent structure is similar to the Chinese medicine theory. It is more objective and is a good way to do the syndrome standard research work. The research gave some support to establish standard for syndrome diagnosis of psoriasis vulgaris.

Key words: latent structure, psoriasis vulgaris, syndrome-element

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