首都医科大学学报 ›› 2014, Vol. 35 ›› Issue (5): 529-532.doi: 10.3969/j.issn.1006-7795.2014.05.001

• 特别关注 • 上一篇    下一篇

浅析埃博拉病毒致病机制

盛子洋, 范东瀛, 安静   

  1. 首都医科大学基础医学院微生物学教研室, 北京 100069
  • 收稿日期:2014-09-12 出版日期:2014-10-21 发布日期:2014-10-20
  • 通讯作者: 范东瀛,安静 E-mail:dengae@ccmu.edu.cn;Anjing@ccmu.edu.cn

Brief summary on pathogenic mechanism of Ebola virus

Sheng Ziyang, Fan Dongying, An Jing   

  1. Department of Microbiology, School of Basic Medical Sciences, Capital Medical University, Beijing 100069, China
  • Received:2014-09-12 Online:2014-10-21 Published:2014-10-20

摘要:

埃博拉病毒(Ebola virus, EBOV)属于丝状病毒科的单股负链RNA病毒,人体感染后可导致致命的埃博拉病毒病(Ebola viral disease, EVD)。当前EBOV广泛流行于非洲大陆,传染性强、致死率高、曾造成多次大暴发,严重威胁着疫区人们的健康和生命。然而目前EBOV的致病机制尚不明确,本文仅就EHF发病机制的最新进展做一综述,供广大同行参考。

关键词: 埃博拉病毒, 出血热, 致病机制

Abstract:

The Ebola virus (EBOV), a single strand negative RNA virus, belongs to Family Filoviridae. The infection can cause severe haemorrhagic fever (EHF). The virus distributes widely in Africa mainland and has caused continuous outbreaks because of its strong virulence and high infectivity. However, the pathogenesis of EHF remains unknown. This review will focus on recent progress of Ebola research to provide information for prevention and treatment of EBOV infection.

Key words: Ebola virus, haemorrhagic fever, pathogenesis

中图分类号: