首都医科大学学报 ›› 2014, Vol. 35 ›› Issue (5): 533-538.doi: 10.3969/j.issn.1006-7795.2014.05.002

• 奖项介绍 • 上一篇    下一篇

2014年拉斯克奖

张婷, 王晓民   

  1. 首都医科大学基础医学院神经生物学系, 北京 100069
  • 收稿日期:2014-09-26 出版日期:2014-10-21 发布日期:2014-10-20
  • 通讯作者: 王晓民 E-mail:xmwang@ccmu.edu.cn
  • 基金资助:

    国家自然科学基金(81200351),北京市自然科学基金(7122065,7112050)。

Lasker Awards 2014

Zhang Ting, Wang Xiaomin   

  1. Department of Neurobiology, School of Basic Medical Sciences, Capital Medical University, Beijing 100069, China
  • Received:2014-09-26 Online:2014-10-21 Published:2014-10-20
  • Supported by:

    This study was supported by National Natural Science Foundation of China(81200351), Natural Science Foundation of Beijing (7122065,7112050).

摘要:

北京时间2014年9月8日,拉斯克奖获奖者名单公布。“基础医学奖”颁发给发现未折叠蛋白反应的Kazutoshi Mori 和Peter Walter,“临床医学奖”颁发给发现丘脑底核的深部脑刺激技术的Alim Louis Benabid 和 Mahlon DeLong,而“特殊贡献奖”则颁发给了对医学和人权富有大胆创见以及多样化贡献的Mary-Claire King。

关键词: 拉斯克奖, 未折叠蛋白反应, 深部脑刺激, BRCA1

Abstract:

In Sep. 8, 2014, Lasker Awards released. The 2014 Albert Lasker Basic Medical Research Award honors Kazutoshi Mori and Peter Walter for their discoveries concerning the unfolded protein response an intracellular quality control system that detects harmful misfolded proteins in the endoplasmic reticulum and signals the nucleus to carry out corrective measures. The 2014 Lasker~DeBakey Clinical Medical Research Award honors Alim-Louis Benabid and Mahlon DeLong for the development of deep brain stimulation of the subthalamic nucleus, a surgical technique that reduces tremors and restores motor function in patients with advanced Parkinson's disease. The 2014 Lasker~Koshland Award for Special Achievement in Medical Science honors Mary-Claire King for bold, imaginative, and diverse contributions to medical science and human rights: she discovered the BRCA1 gene locus that causes hereditary breast cancer and deployed DNA strategies that reunite missing persons or their remains with their families.

Key words: Lasker Awards, unfolded protein response, deep brain stimulation, BRCA1