首都医科大学学报 ›› 1995, Vol. 16 ›› Issue (3): 172-175.

• 论著 • 上一篇    下一篇

小鼠单侧卵巢自体异位移植

梁元晶, 诸定寿, 史小林   

  1. 首都医学院生殖医学中心
  • 收稿日期:1994-04-22 修回日期:1900-01-01 出版日期:1995-07-15 发布日期:1995-07-15

A Morphological Study on the Unilateral Autotransplanted Ovary in Mice

Liang Yuanjing, Zhu Dingshou, Shi Xiaolin   

  1. Department of Reproductive Medicine, Capital Institute of Medicine
  • Received:1994-04-22 Revised:1900-01-01 Online:1995-07-15 Published:1995-07-15

摘要:

生后20~35d小鼠进行单侧卵巢自体皮下移植。原位卵巢发育正常。异位移植卵巢外包较厚的结缔组织膜。卵泡坏死始于移植第2d.第4d卵巢皮质浅层见大量原始卵泡,坏死灶内出现大量血细胞。第7d卵集中可见新生的窦前卵泡。第14d卵泡生长,坏死组织纤维化。第28d卵巢中出现较多发育不同阶段的卵泡、黄体和间质腺样组织。实验显示移植卵巢能够存活、发育并分泌性激素。

关键词: 小鼠, 卵巢, 移植

Abstract:

One ovary of the mouse aged 20 to 35 postnatal days was autotransplanted subcutaneously.The orthotopic ovary developed normally. The grafted ovary was found to be surrounded by a thick layer of connective tissue. Follicular necrosis began 2 days after transplantation. Alot of primodial follicles existed in the ovarian cortex on day 4. Numerous blood cells infiltrated in the necrotic area. Preantral follicles were found on day 7. On day 14 after transplantation,follicles developed and necrosis was changed to fibrous tissue. On the 28th day, many follicles in different stages of development, corpora lutea and interstitial gland could be detected. This study shows that the transplanted ovary can grow well and secret steroid hormones.

Key words: mouse, ovary, transplantation

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