胶原酶注射治疗腰椎间盘突出症32例随访报告

首都医科大学学报 ›› 1999, Vol. 20 ›› Issue (2): 121-122.

胶原酶注射治疗腰椎间盘突出症32例随访报告

邵翔绪¹, 卢思奇²

1. 北京市宣武中医院骨科;2. 首都医科大学细胞生物学系

收稿日期:1998-10-26 修回日期:1900-01-01 出版日期:1999-04-15 发布日期:1999-04-15

The Treatment of Lumbar Intervertebral Disc Protrusion Using Collagenase Injection Follow up Report of 32 Cases

Shao Xiangxu¹, Lu Siqi²

1. Department of Orthopedics, Beijing Xuanwu Hospital of Traditional Chinese Medicine;2. Department of Cell Biology, Capital University of Medical Sciences

Received:1998-10-26 Revised:1900-01-01 Online:1999-04-15 Published:1999-04-15

摘要/Abstract

摘要： 为了解胶原酶治疗腰椎间盘突出症的远期疗效,对32例病人进行了随访。其中15例将胶原酶400～600U注入病变椎间盘内(盘内注射法);17例将胶原酶600～1200U注入病变椎间盘的椎间孔附近的硬膜外间隙(盘外注射法).3年随访结果为:优17例、良2例、可6例、劣7例(其中4例又做开放椎间盘髓核摘除术).优良率59.4%,有效率78.1%,再手术率为12.5%,未发现明显并发症。

关键词: 胶原酶, 髓核溶解术, 椎间盘突出, 盘内注射, 盘外注射

Abstract: To evaluate the forward therapeutic effect of chemonucleolysis using collagenase for the treatment of lumbar intervertebral disc protrusion, a follow up survey of 32 cases was made. All the patients were hospitalized and treated with this method. Of the cases, 15 were treated with :“intradisc injection method”, i. e. the injection with 400～600 U of the enzyme was given into the intervertebral disc and 17 with extradisc injection method, i. e. the injection with 600～1200 U of the enzyme was given into the extradural space. Results: 17 showed excellent results, 2 good, 6 fair and 7 poor. Totally, the injection treatment of collagenase gave an excellent and good rate of 59.4%, and an effective rate of 78.1%. The surgical exploration rate was 12.5%.

Key words: lumber intervertebral disc protrusion, collagenase, chemonucleolysis, intradisc injection, extradisc injection

中图分类号:

R681.53

邵翔绪;卢思奇. 胶原酶注射治疗腰椎间盘突出症32例随访报告[J]. 首都医科大学学报, 1999, 20(2): 121-122.

Shao Xiangxu;Lu Siqi. The Treatment of Lumbar Intervertebral Disc Protrusion Using Collagenase Injection Follow up Report of 32 Cases[J]. Journal of Capital Medical University, 1999, 20(2): 121-122.

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