肝炎后肝硬化和重型肝炎患者血小板4项指标的测定意义

首都医科大学学报 ›› 2000, Vol. 21 ›› Issue (4): 304-306.

肝炎后肝硬化和重型肝炎患者血小板4项指标的测定意义

黄康龄, 陈晓, 李在村, 郭庆良, 汪俊韬

北京佑安医院七病区

收稿日期:1999-05-19 修回日期:1900-01-01 出版日期:2000-10-15 发布日期:2000-10-15

Clinical Significance of Four Parameters of Platelet in Patients with Liver Cirrhosis and Severe Hepatitis

Huang Kangling, Chen Xiao, Li Zaicun, Guo Qingliang, Wang Juntao

Beijing You′an Hospital

Received:1999-05-19 Revised:1900-01-01 Online:2000-10-15 Published:2000-10-15

摘要/Abstract

摘要： 采用日本东亚SysmexF800型血细胞自动计数仪检测了150例肝炎后肝硬化、150例重型肝炎、114例急性黄疸型肝炎、107例慢性活动型肝炎和50例健康成人的血小板功能4项指标：血小板计数(BPC)、平均血小板体积(MPV)、血小板压积(PCT)和血小板分布宽度(PDW).结果显示：肝炎后肝硬化组和重型肝炎组患者的BPC和PCT值均显着降低(P<0.05或P<0.01),特别是2组中的死亡与明显出血者降低更显着(P<0.05或P<0.01).提示血小板的4项指标除间接反映血小板的功能外,对评估病毒性肝炎的严重程度、出血倾向有重要的辅助指导意义.

关键词: 肝炎后肝硬化, 重型肝炎, 血小板功能

Abstract: To explore the clinical significance of four parameters of platelet in patients with liver cirrhosis and severe hepatitis. 521 patients with varied types of viral hepatitis were divided into 2 observing groups (liver cirrhosis and severe hepatitis) and 3 controlled groups (chronic active hepatitis, acute hepatitis and healthy adult). Four parameters of platelet (PLT, MPV, PCT and PDW) were detected (using Japan East Asia Sysmex F 800 hematocyte automatic counting machine) and compared. PLT and PCT in patients with liver cirrhosis and severe hepatitis decreased significantly (P<0.05 or P<0.01), especially in those who died or bled obviously. This suggested that the four parameters of platelet can not only reflex platelet function, but also help evaluate the severity and hemorrhage trend of viral hepatitis.

Key words: liver cirrhosis, sever hepatitis, platelet function

中图分类号:

黄康龄;陈晓;李在村;郭庆良;汪俊韬. 肝炎后肝硬化和重型肝炎患者血小板4项指标的测定意义[J]. 首都医科大学学报, 2000, 21(4): 304-306.

Huang Kangling;Chen Xiao;Li Zaicun;Guo Qingliang;Wang Juntao. Clinical Significance of Four Parameters of Platelet in Patients with Liver Cirrhosis and Severe Hepatitis[J]. Journal of Capital Medical University, 2000, 21(4): 304-306.

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