首都医科大学学报 ›› 2001, Vol. 22 ›› Issue (3): 220-221.

• 论著 • 上一篇    下一篇

比索洛尔治疗轻、中度原发性高血压的临床研究

赵秀丽, 胡大一, 贾三庆, 高明明, 韩献华, 顼志敏   

  1. 首都医科大学附属北京红十字朝阳医院心脏中心
  • 收稿日期:2001-02-23 修回日期:1900-01-01 出版日期:2001-07-15 发布日期:2001-07-15

Antihypertensive Effects of Bisoprolol on Hypertensive Patients

Zhao Xiuli, Hu Dayi, Jia Sanqing, Gao Mingming, Han Xianhua, Xu Zhimin   

  1. Department of Heart Center, Beijing Red Cross Chaoyang Hospital, Affiliate of Capital University of Medical Sciences
  • Received:2001-02-23 Revised:1900-01-01 Online:2001-07-15 Published:2001-07-15

摘要: 为评价比索洛尔治疗轻、中度原发性高血压的疗效和安全性,用比索洛尔(5~10mg),1/d,共用8周,治疗轻、中度原发性高血压患者30例,并用24h动态血压监测评价用药前及8周治疗后24h血压的变化.结果:29例完成治疗随访的患者中,降压总有效率达86.2%,与用药前相比,治疗后的收缩压与舒张压均显着降低,谷/峰比值>50%,不良反应少,对血脂和血糖水平无影响.提示,比索洛尔降低轻、中度原发性高血压病人血压的疗效确切.

关键词: 比索洛尔, 高血压, 动态血压监测

Abstract: To evaluate the antihypertensive effect and safety of bisoprolol, 30 patients with mild to moderate primary hypertension were treated with bisoprolol 5 to 10 mg, once daily for 8 weeks. It were also monitored that changes of blood pressure before and after medicine by 24 h ambulatory blood pressure monitoring. 29 cases were followed up. The total effectiveness was 86.2%. Compared with pre treatment, the decreased SBP and DBP had significant statistical difference. The T/P ratio was >50%. The adverse effect was low, and there was no side effect on the metabolic of cholesterol and glucose . The results shows that bisoprolol is effective and safe in the treatment of mild to moderate primary hypertension.

Key words: bisoprolol, primary hypertension, ABPM

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