首都医科大学学报 ›› 2003, Vol. 24 ›› Issue (1): 54-55.

• 论著·临床研究 • 上一篇    下一篇

原发性高血压患者眼底改变与动态血压关系的研究

邸茹杰1, 华琦1, 邢绣荣1, 皮林1, 吴航2   

  1. 1. 首都医科大学宣武医院心内科;2. 首都医科大学宣武医院眼科
  • 收稿日期:2002-02-18 修回日期:1900-01-01 出版日期:2003-01-15 发布日期:2003-01-15

Relationships between Retinal Arteriosclerosis and Essential Hypertension

Di Rujie1, Hua Qi1, Xing Xiourong1, Pi Lin1, Wu Hang2   

  1. 1. Department of Cardiovascular, Xuanwu Hospital, Affiliate of Capital University of Medical Sciences;2. Department of Ophthalmolog, Xuanwu Hospital, Affiliate of Capital University of Medical Sciences
  • Received:2002-02-18 Revised:1900-01-01 Online:2003-01-15 Published:2003-01-15

摘要: 为了探讨原发性高血压(以下简称高血压)患者血压与眼底改变的关系,分别观察186例轻中度高血压患者的脉压、诊所舒张压、24h平均舒张压、血压负荷及夜间血压下降率与眼底小动脉改变的关系。结果:186例患者中,眼底正常46例(24.7%),Ⅰ级改变116例(62.4%),Ⅱ级改变24例(12.9%).眼底正常组左室肥厚(LVH)的发生率为10.9%(5/46),而眼底异常组的发生率为89.3%(125/140).诊所舒张压≥13.3kPa(100mmHg)、24h舒张压≥12.0kPa(90mmHg)的高血压组与其对应组相比眼底改变有显着性差异(P分别<0.05、<0.01);舒张期血压负荷超过40%组与对应组比较眼底改变有显着性差异(P<0.05),而收缩压负荷、杓型与非杓型血压及不同脉压差组的眼底变化组间比较无显着性差异(P>0.05).提示:无合并症的轻中度高血压患者早期眼底改变大多为Ⅰ级,受舒张压的影响较明显,视网膜动脉硬化的程度也提示高血压的时限及病情。

关键词: 脉压, 原发性高血压, 视网膜眼底动脉

Abstract: The aim of the present study was to assess the risk of retinal arteriosclerosis at different ambulatory blood pressures (ABP) in essential hypertensive patients. Subjects were males and females, aged between 14 and 73 years, suffering from mild to moderate essential hypertension. BPdata was obtained by using Spacelabs monitors for a full 24 h. The retinal artery were examined using fundscope. The results showed significant differences in the degree of retinal arteriosclerosis between groups with different clinical diastolic blood pressure (DBP) and different DBPL (P<0.05). No similar finding was between retinal artery and the difference of pulse pressure and night BPdecreasing rate. The proportion of first grade retinal arteriosclerosis in hypertensives patient was 62.4%. It is suggested that retinal arteriosclerosis(gradeⅠ) was more closely related with DBP in most of the subjects suffering from mild to moderate essential hypertension, coexisted with LVH.

Key words: pulse pressure, essential hypertension, retinal arteriosclerosis

中图分类号: