关键词: 连续性动静脉血液滤过, 肾移植, 急性左心功能不全, 多脏器功能衰竭

Abstract: To observe the aim of this study was to explore the practical approach for treating patients with CAVH. Eighty-nine kidney transplant recipients were studied. All patients were treated with CAVH (dialysate flow rate is 2 L/h). Whole or washed blood cells or plasm were re-circulated at 25-45 mL/min through a 1.4m² polysulfones hemofilters for 4～8 h with filtration. In every 30 min 10 mLof 10% NaCl was infused into the circulation. Immunosuppressive agents were used continuously during that period. Blood and albumin were also used. Each measurement was performed immediately before and every 30 min after commencement of technique of filtration. The main measurement included heart rate, blood pressure, output of filtrated water, cytokine, allograf t function, blood-gas and chest X-ray. Results: 67 cases with renal and heart function recovered well and 78 cases with renal allograf t recovered well after 1 to 2 years. Four patients were on regular dialysis. Eleven patients died of multi-organ failure (MOF). The use of CAVH would reduce vascular volume, extra-cellular or intracellular fluid volume. It could reduce renal allograf t edema without affecting blood pressure and electrolyte, and improve allograft function and pulmonary alveolus ventilation. CAVH is safe, effective, simple and convenient.

Key words: CAVH, renal transplant, acute left heart failure, MOF