首都医科大学学报 ›› 2003, Vol. 24 ›› Issue (2): 184-186.

• 论著·临床研究 • 上一篇    下一篇

平阳霉素囊内化疗治疗囊性颅咽管瘤

姚红新, 马振宇, 罗世祺   

  1. 首都医科大学附属北京天坛医院神经外科
  • 收稿日期:2002-04-11 修回日期:1900-01-01 出版日期:2003-04-15 发布日期:2003-04-15

Cysitic Craniopharyngioma Chemotherapy with Intratumoral Injections of Pingyangmycin

Yao Hongxin, Ma Zhenyu, Luo Shiqi   

  1. Department of Neurosurgery, Beijing Tiantan Hospital, Affiliate of Capital University of Medical Sciences
  • Received:2002-04-11 Revised:1900-01-01 Online:2003-04-15 Published:2003-04-15

摘要: 使用平阳霉素对5例囊性颅咽管瘤患者进行单纯囊内化疗,开颅将Ommaya储液管头端置于肿瘤囊内,储液囊埋在皮下。通过储液囊抽取囊液监测乳酸脱氢酶(LDH)和囊液颜色变化,并注入平阳霉素。结果:5例囊性颅咽管瘤中有3例肿瘤消失,2例有效。其中1例出现脑神经损害症状。

关键词: 颅咽管瘤, 化疗, 平阳霉素

Abstract: Five patients who suffered cysitic craniopharyngioma were admitted. The tube of Ommaya reservoir was inserted into the cyst, and the Ommaya reservoir was placed beneath the scalp for delivery of chemotherapy. The colors and LDH of the liquid in the tumors were studied, then pingyangmycin (bleomycin A5) was injected into the cysitic tumor. Three of the five cysitic craniopharyngioma were complete regressed, the other two cases were shrinked. There was one case showing symptoms of cranial nerve damage. The outcome indicated that the local injection of pingyangmycin was effective against tumors of the cystic type.

Key words: craniopharyngioma, chemotherapy, pingyangmycin

中图分类号: