首都医科大学学报 ›› 2007, Vol. 28 ›› Issue (6): 766-769.

• 临床研究 • 上一篇    下一篇

男性糖尿病患者勃起功能与睾酮、泌乳素水平关系的初步探讨

信中, 袁申元, 王召平, 谢荣荣, 杨金奎   

  1. 首都医科大学附属北京同仁医院内分泌科
  • 收稿日期:2007-02-25 修回日期:1900-01-01 出版日期:2007-12-24 发布日期:2007-12-24
  • 通讯作者: 杨金奎

The Relationship between Erectile Dysfunction and Testosterone,Prolactin in Men with Type 2 Diabetes Mellitus

Xin Zhong, Yuan Shenyuan, Wang Zhaoping, Xie Rongrong, Yang Jinkui   

  1. Department of Endocrinology, Beijing Tongren Hospital, Capital Medical University
  • Received:2007-02-25 Revised:1900-01-01 Online:2007-12-24 Published:2007-12-24

摘要: 目的 探讨男性2型糖尿病患者勃起功能障碍(ED)与睾酮(T)及泌乳素(PRL)水平的关系。方法 以问卷调查的方法比较了60名2型糖尿病患者及51名非糖尿病人群国际勃起功能指数(IIEF)评分的差异,并测定了2组人群的血清总睾酮(TT)及PRL水平。结果 男性2型糖尿病患者IIEF评分及TT水平显著低于对照组,差异有统计学意义(P<0.001),PRL水平显著高于对照组,差异亦有统计学意义(P<0.001)。结论 男性2型糖尿病患者中存在着性腺功能及勃起功能的减退,糖尿病患者勃起功能障碍不但与内分泌激素(T、PRL)的异常有关,也与糖尿病病程等因素有关。提示对男性糖尿病合并ED的患者有必要检测性激素以指导治疗;性激素异常与糖尿病之间的关系需进一步探讨。

关键词: 2型糖尿病, 国际勃起功能指数, 睾酮, 泌乳素

Abstract: Objective To study the relationship between erectile dysfunction(ED) and the abnormalities of testosterone(T) and Prolactin(PRL) levels in type 2 diabetes mellitus(T2DM) in men.Methods Erectile function(EF) of 60 men with T2DM and a control group of 51 non-diabetic men were assessed with the International Index of Erectile Function(IIEF).Venous blood was drawn for the determination of T and PRL.Results The IIEF scores and values of total testosterone(TT) in diabetic men were significantly lower than those of the controls(P<0.001) and the values of PRL were significantly higher than those of the controls(P<0.001).Conclusion There are hypogonadism and ED in men with T2DM.Diabetic ED closely correlates not only with the sex hormone(T and PRL),but also with the diabetic duration and hypertension.It is very important to examine the sex hormone level in diabetic men with T2DM with ED.The relationship between T2DM and sex hormone needs further research.

Key words: type 2 diabetes mellitus, International Index of Erectile Function, testosterone, prolactin

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