关键词: 血小板活化, 冠心病, 血瘀证, 血小板膜糖蛋白

Abstract: The platelet membrane glycoprotein plays a key role in the adhesion,aggregation and release of platelets,and is the specific marker for platelet activation.Many studies have shown that the activity of the platelet membrane glycoprotein,especially CD62P,CD63 and PAC-1,can reflect the pathogenesis and development of coronary heart disease sensitively and specifically,and its expression can be influenced by the pathological conditions.Blood-stasis syndrome is one of the most common clinical syndromes.Patients having different diseases with blood-stasis syndrome do have platelet activation,but in terms of the platelet activity,there is no difference among them.Measurement of the activated platelet membrane glycoprotein not only provides help to diagnose acute myocardial infarction sooner and estimate the state of the illness,but also can be served as one of the indicators of micro-dialectical discrimination of illness.

Key words: platelet activation, coronary heart disease, blood-stasis syndrome, platelet membrane glycoprotein