颅脑手术中脑认知功能保护的微创神经外科学基础研究——与临床应用2009年度国家科学技术进步二等奖

首都医科大学学报 ›› 2010, Vol. 31 ›› Issue (1): 8-10.

颅脑手术中脑认知功能保护的微创神经外科学基础研究——与临床应用2009年度国家科学技术进步二等奖

赵继宗, 曹勇, 唐亚娟

首都医科大学附属北京天坛医院神经外科

收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2010-02-21 发布日期:2010-02-21

The Second Grade National Prize for Science and Technology Progress

ZHAO Ji-zong, CAO Yong, TANG Ya-juan

Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University

Received:1900-01-01 Revised:1900-01-01 Online:2010-02-21 Published:2010-02-21

摘要/Abstract

摘要： 20世纪末世界神经外科进入微创神经外科时代，颅脑解剖结构和神经功能双重保护的全新理念，向当时还处于显微神经外科时代的中国神经外科医师发出挑战。为引领我国神经外科学进入国际先进行列，本课题组在国内率先实践微创神经外科理念，建立微创神经外科学技术平台，普及和推广规范的微创神经外科治疗理念，并在国家十五攻关项目《脑卒中规范化外科治疗技术推广研究》得到实践。课题组从搭建规范化微创神经外科技术平台、精确定位颅脑手术中神经功能与解剖结构之间相互关系等方面着手，以“最小创伤性操作处理病灶，最大限度保护或恢复神经功能”为基本原则，应用微创技术改变传统开颅手术模式，实现了准确的病灶解剖和脑认知功能定位；整合脑血流和神经电生理等手术中监测技术，建立脑功能保护预警系统。同时体现了转化医学理念，首次将脑认知功能基础研究结果直接应用于颅脑手术，不仅最大限度保护患者肢体运动、语言和基本视觉功能，而且在国际上首次验证了中文语言区和颞叶前区的拓扑功能。应用本研究成果极大地改善了全国颅脑手术患者预后，降低了患者的治疗费用，促进了我国的微创神经外科水平进入国际先进行列。

关键词: 国家科学技术进步奖, 微创神经外科学, 脑认知, 神经导航

Abstract: In the last decade of the 20th century, the protection of both structure and function of brain in brain surgery had become a typical principle in the field of minimally invasive neurosurgery worldwide. However, brain surgery in China was still in the stage of micro-neurosurgery at that time. This study was to popularize the concept and technologies of minimally invasive neurosurgery in the treatment of brain surgery throughout the country. Based on the principle of “the least injury, the largest preservation of brain function”, traditional craniotomies were improved, and a set of both intraoperative monitoring and alerting system for brain protection were established as well. Meanwhile, the application of transitional medicine helped greatly to protect the basic visual, lingual and motor functions of the brain in neurosurgery. We are the first to verify the functional topology of the Chinese linguistic areas and the anterior region of the temporal lobe in the world, based on both scientific and clinical works. This study helped to improve the outcome of patients receiving minimally invasive neurosurgery in China, and lower the cost of the treatment of the diseases. Brain surgery in China has reached the international level in the field of minimally invasive neurosurgery.

Key words: National Prize for Science and Technology Progress, minimally invasive neurosurgery, brain and cognitive science, neuronavigation

中图分类号:

R 651

赵继宗;曹勇;唐亚娟. 颅脑手术中脑认知功能保护的微创神经外科学基础研究——与临床应用2009年度国家科学技术进步二等奖[J]. 首都医科大学学报, 2010, 31(1): 8-10.

ZHAO Ji-zong;CAO Yong;TANG Ya-juan. The Second Grade National Prize for Science and Technology Progress[J]. Journal of Capital Medical University, 2010, 31(1): 8-10.