人工耳蜗植入者失匹配负波的特征研究

首都医科大学学报 ›› 2011, Vol. 32 ›› Issue (1): 50-54.

• 耳鼻咽喉头颈外科基础与临床研究 • 上一篇下一篇

人工耳蜗植入者失匹配负波的特征研究

康慧^1，2，龚树生^1，2*，陈雪清^1,2，刘莎^1,2

1. 首都医科大学附属北京同仁医院耳鼻咽喉头颈外科； 2. 教育部耳鼻咽喉头颈外科重点实验室，北京市耳鼻咽喉科研究所

收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2011-02-21 发布日期:2011-02-21
通讯作者: 龚树生

Analysis of Mismatch Negativity in Cochlear Implant Users

KANG Hui^1,2, GONG Shu-sheng^1,2*, CHEN Xue-qing^1,2, LIU Sha^1,2

1. Department of Otorhinolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University; 2. Key Laboratory of Otorhinolaryngology Head and Neck Surgery, Ministry of Education, Beijing Institute of Otorhinolaryngology

Received:1900-01-01 Revised:1900-01-01 Online:2011-02-21 Published:2011-02-21
Contact: GONG Shu-sheng

摘要/Abstract

摘要：

目的初步研究人工耳蜗植入者在言语声刺激下引出失匹配负波（mismatch negativity，MMN）的波形表现及相关意义。
方法采用经典Oddball模式，以/ba/和da/的言语声为标准刺激和偏差刺激，测量人工耳蜗植入组及正常对照组MMN，分析2组受试者MMN潜伏期及波幅、言语识别得分及平均听阈的相关性。
结果人工耳蜗植入组与正常对照组MMN潜伏期差异具有统计学意义，而波幅差异无统计学意义。人工耳蜗植入组中，言语识别得分与MMN潜伏期及波幅相关性有显著意义。
结论 MMN潜伏期、波幅均与言语识别得分相关性显著，即可作为一项客观检查，为判断人工耳蜗植入后患者言语识别能力提供客观依据。

关键词: 人工耳蜗, 失匹配负波, 事件相关电位

Abstract:

Objective To investigate the characteristics of the cochlear implant users on mismatch negativity(MMN).
Methods The standard(/ba/) and deviant stimuli (/da/) were presented in an oddball paradigm and the MMN were recorded. The relevance among the scores of speech discrimination and the characters of MMN and the mean auditory thresholds were investigated.
Results The peak latency of MMN in the cochlear implant(CI) group was significantly longer than that in the control group, but the amplitude changed slightly. A significant correlation was found between the scores of speech discrimination and the characters of MMN in CI group.
Conclusion There was significant correlation among the scores of speech discrimination and MMN, which further confirmed that mismatch negativity is a tool for the assessment of stimuli discrimination in cochlear implant subjects.

Key words: cochlear implant, mismatch negativity, event related potentials

中图分类号:

R 764.35

康慧;龚树生;陈雪清;刘莎. 人工耳蜗植入者失匹配负波的特征研究[J]. 首都医科大学学报, 2011, 32(1): 50-54.

KANG Hui;GONG Shu-sheng;CHEN Xue-qing;LIU Sha;. Analysis of Mismatch Negativity in Cochlear Implant Users[J]. Journal of Capital Medical University, 2011, 32(1): 50-54.

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[2]	刘博;董瑞娟;陈雪清;龚树生;李永新;郑军;韩德民. 大前庭水管综合征人工耳蜗植入者的听力特点与效果分析[J]. 首都医科大学学报, 2009, 30(6): 752-756.
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人工耳蜗植入者失匹配负波的特征研究

Analysis of Mismatch Negativity in Cochlear Implant Users

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