首都医科大学学报 ›› 2016, Vol. 37 ›› Issue (5): 583-587.doi: 10.3969/j.issn.1006-7795.2016.05.005

• 呼吸疾病基础与临床 • 上一篇    下一篇

慢性阻塞性肺疾病患者血浆脑钠肽增高的机制

苗苗, 卜小宁   

  1. 首都医科大学附属北京朝阳医院呼吸与危重症医学科, 北京100020
  • 收稿日期:2016-06-30 出版日期:2016-10-21 发布日期:2016-10-19
  • 通讯作者: 卜小宁 E-mail:13641000837@163.com
  • 基金资助:
    北京市新星计划(2008B27)。

Mechanism of the increased level of plasma brain type natriuretic peptide in chronic obstructive pulmonary disease

Miao miao, Bu Xiaoning   

  1. Department of Pulmonary and Critical Care Medicine, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China
  • Received:2016-06-30 Online:2016-10-21 Published:2016-10-19
  • Supported by:
    This study was supported by Beijing Rising Star Project(2008B27).

摘要: 慢性阻塞性肺疾病是一种炎性反应性疾病,这种炎性反应可累及心血管系统,导致慢性阻塞性肺疾病患者心血管疾病的发生率增加,心脏标志物脑钠肽及其前体与慢性阻塞性肺疾病的相关研究成为热点。本文就慢性阻塞性肺疾病患者血浆脑钠肽增高的机制予以综述。

关键词: 慢性阻塞性肺疾病, 脑钠肽, 肺过度充气, 炎性反应

Abstract: Chronic obstructive pulmonary disease (COPD) is an inflammatory disease which can affect the cardiovascular system resulting in an increased incidence of cardiovascular disease in COPD. The relationship between the cardiac markers such as brain type natriuretic peptide (BNP) and its precursor and COPD becomes a hot topic. This article reviews the mechanism of the increased level of plasma BNP in patients with COPD.

Key words: chronic obstructive pulmonary disease, brain type natriuretic peptide, hyperinflation, inflammation

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