围绝经期及绝经后女性性功能障碍状况及与更年期症状的关系分析

doi:10.3969/j.issn.1006-7795.2020.04.001

首都医科大学学报 ›› 2020, Vol. 41 ›› Issue (4): 503-507.doi: 10.3969/j.issn.1006-7795.2020.04.001

围绝经期及绝经后女性性功能障碍状况及与更年期症状的关系分析

鞠蕊¹, 阮祥燕¹, 许新¹, 杨瑜¹, 张露平¹, 秦爽¹, 王宾红¹, 豆竹丽¹, Alfred O. Mueck^1,2

1. 首都医科大学附属北京妇产医院内分泌科, 北京 100026;
2. 德国图宾根大学妇产医院妇女健康部与妇女健康研究中心, 图宾根D-72076, 德国

收稿日期:2020-05-08 出版日期:2020-08-21 发布日期:2020-07-22
通讯作者: 阮祥燕 E-mail:ruanxiangyan@163.com
基金资助:
北京市医院管理局"登峰"计划专项（DFL20181401），首批北京市级妇幼保健专科示范单位"更年期保健专科"建设与管理项目（2018/01-2020/12），中国健康促进基金会项目（CHPF-2018-OP-11），中国国际人才交流促进会医疗健康技术创新与人才培养专项基金（2017041900004，2018042000001）。

Prevalence of female sexual dysfunction and the relationship between climacteric symptoms and female sexual dysfunction in Chinese women with menopause transition stage and postmenopausal stage

Ju Rui¹, Ruan Xiangyan¹, Xu Xin¹, Yang Yu¹, Zhang Luping¹, Qin Shuang¹, Wang Binhong¹, Dou Zhuli¹, Alfred O. Mueck^1,2

1. Department of Gynecological Endocrinology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing 100026, China;
2. Department of Women's Health, University Women's Hospital and Research Centre for Women's Health, University of Tuebingen, Tuebingen D-72076, Germany

Received:2020-05-08 Online:2020-08-21 Published:2020-07-22
Supported by:
This study was supported by Beijing Municipal Administration of Hospitals' Ascent Plan(DFL20181401),The First Batch of Beijing Maternal And Child Health Specialist Demonstration Units Menopausal Health Specialist (2018/01-2020/12),China Health Promotion Foundation (CHPF-2018-OP-11), China International Talent Exchange Association Medical Health Technology Innovation and Talent Training Special Fund(2017041900004,2018042000001).

摘要/Abstract

摘要： 目的调查围绝经期及绝经后女性性功能障碍状况，分析更年期症状对女性性功能障碍（female sexual dysfunction，FSD）的影响。方法选取2019年6月至2019年10月在首都医科大学附属北京妇产医院内分泌科就诊的40岁以上女性180例进行问卷调查，根据生殖衰老分期研讨会（Stages of Reproductive Aging Workshop，STRAW+10）标准将研究对象分为4组：绝经过渡早期（A组）、绝经过渡晚期（B组）、绝经后期早期（C组）、绝经后期晚期（D组）。应用改良Kupperman评分表（Modified Kupperman Index，KMI）评价女性更年期症状；女性性功能指数（Female Sexual Function Index，FSFI）量表评价女性性功能障碍。结果随着生殖衰老分期的提高，4组患者的年龄中位数逐渐增大，从45.5岁提高到57.0岁；与伴侣共同生活时间的年限中位数从20年增加到23.5年，性生活的间隔时间中位数从7 d增加到15 d；KMI中位数从9.5分提高到15分（P<0.05）。随着生殖衰老分期的升高，FSD和性欲障碍、性唤起障碍、阴道湿润障碍、性高潮障碍、性满意度障碍和性交痛的患病率均明显升高（P<0.05）。FSD和性欲障碍、性唤起障碍、阴道湿润障碍、性高潮障碍、性满意度障碍和性交痛的患病率随更年期症状的严重程度提高而升高（P<0.05）。结论随着女性生殖衰老分期的提高，FSD的患病率明显升高。出现更年期症状以及其严重程度是40岁以上女性发生FSD的重要影响因素，应积极治疗更年期症状以提高女性的生活质量。

关键词: 更年期症状, 女性性功能障碍, 绝经, 女性健康

Abstract: Objective To investigate the effects of climacteric symptoms on female sexual dysfunction(FSD) at different reproductive aging stages. Methods A cross-sectional study including 180 cases was conducted among women over 40 years old in the Department of Gynecological Endocrinology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, China, from Jun. 2019 to Oct. 2019. According to the 2011 stages of the Reproductive Ageing Workshop (STRAW+10), the subjects were divided into four groups:early menopausal transition stage (group A), late menopausal transition stage (group B), early postmenopausal stage (group C), and late postmenopausal stage (group D). Female climacteric symptoms were evaluated by Modified Kupperman Index (KMI), and FSD was evaluated by Female Sexual Function Index (FSFI). Results With the increase of stages of the reproductive aging, the median age of the subjects increased from 45.5 years to 57.0 years, the median years of cohabitation with their partners increased from 20 years to 23.5 years, the median time of sexual frequency increased from 7 days to 15 days, and the median KMI increased from 9.5 to 15 days (P<0.05). With the increase of stages of the reproductive aging, the prevalence of FSD and sexual desire disorder, sexual arousal disorder, vaginal lubrication disorder, orgasm disorder, sexual satisfaction disorder, and vaginal pain were significantly increased (P<0.05). The prevalence of FSD and sexual desire disorder, sexual arousal disorder, vaginal lubrication disorder, orgasm disorder, sexual satisfaction disorder, and vaginal pain increased with the severity of menopausal symptoms (P<0.05). Conclusion With advanced stage of reproductive aging, FSD was prevalent significantly. The prevalence of FSD was higher in women with menopausal symptoms. The more severe the menopausal symptoms were, the higher the prevalence of FSD was. Climacteric symptoms and their severity are important factors affecting the occurrence of FSD in women over 40 years old. Climacteric symptoms should be actively treated to improve the quality of life of women.

Key words: climacteric, female sexual dysfunction, menopause, women's health

中图分类号:

R711

鞠蕊, 阮祥燕, 许新, 杨瑜, 张露平, 秦爽, 王宾红, 豆竹丽, Alfred O. Mueck. 围绝经期及绝经后女性性功能障碍状况及与更年期症状的关系分析[J]. 首都医科大学学报, 2020, 41(4): 503-507.

Ju Rui, Ruan Xiangyan, Xu Xin, Yang Yu, Zhang Luping, Qin Shuang, Wang Binhong, Dou Zhuli, Alfred O. Mueck. Prevalence of female sexual dysfunction and the relationship between climacteric symptoms and female sexual dysfunction in Chinese women with menopause transition stage and postmenopausal stage[J]. Journal of Capital Medical University, 2020, 41(4): 503-507.

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围绝经期及绝经后女性性功能障碍状况及与更年期症状的关系分析

Prevalence of female sexual dysfunction and the relationship between climacteric symptoms and female sexual dysfunction in Chinese women with menopause transition stage and postmenopausal stage

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