首都医科大学学报 ›› 1991, Vol. 12 ›› Issue (4): 296-298.

• 论著 • 上一篇    下一篇

糖尿病B淋巴细胞株超微形态

洪明理, 李哲先, 付治锋, 尔秀江, 李云生, 毕如玫, 童洁, 徐秀红, 任家强, 贾宝祥   

  1. 北京友谊医院 北京市临床医学研究所
  • 收稿日期:1991-03-04 修回日期:1900-01-01 出版日期:1991-10-15 发布日期:1991-10-15

Ultrastructure of B Lymphocytoid Cell Lines of Patients with Diabetes

Hong Mingli, Li Zhexian   

  1. Beijing Institute of Clinical Medicine, Beijing Friendship Hospital
  • Received:1991-03-04 Revised:1900-01-01 Online:1991-10-15 Published:1991-10-15

摘要: 电镜观察了8例EB病毒转化的糖尿病患者B淋巴细胞株和2例正常人B淋巴细胞。见糖尿病B淋巴细胞株的细胞与PHA刺激转化的淋巴母细胞以及EB病毒引起的Burkitt淋巴瘤细胞明显不同.而与文献报道的携带EB病毒的二倍体B淋巴细胞类似。但糖尿病B淋巴细胞株的细胞明显呈多形性.而且分裂增殖和运动更活跃,并具有吞噬活性.

关键词: 糖尿病, B 淋巴细胞株, 超微形态

Abstract: Blymphocytoid cell lines of 8 patients with diabetes and 2 Control have been studied.It was found that the ultrastructure of Blymphocytoid cell line from patients with diabetes, was different from PHA-stimulated lymphocytoid cell and Burkitt's lymphomd cells,but it was similar to EBV-carring diploid lymphoblastoid cells in literature published.Significant pleomorphism,more active cell division,proliferation,motility and phagocytosis have been observed in these cell lines.

Key words: diabetes, B lympheytoid cell line, ultrastructure