关键词: 高龄, 尿毒症, 肾移植

Abstract: Fifty one uremic patients over 60 who received cadaveric renal transplantation were retrospectively analyzed in order to investigate the renal transplantation in the aged uremic patients. Results: the survival rate of person/kidney one year was 88.2%/86.2%. Two patients died from the acute tubular necrosis and heart failure and lung infection, one patient died from the severe pneumonia while the other one died from cerebrovascular accident. The total complications post transplantation included one hyperacute rejection, four acute rejection, two chronic rejection, four acute tubular necrosis, 13 hepatotoxicity and nephrotoxicity of cyclosporin A, six leukopenia, 2 posttransplant diabetes mellitus, 9 lung infection, eight heart failure and one fistula in the ureterocystanastomosis. Therefore, the advanced patients are still suitable for the renal transplantation. It special attention has to be paid on the treatment of infection and cardiovascular diseases and nursing care, and it is also important to adjust and monitor the toxic side effects of the immunosuppressive drugs, and the dose of CsA in the aged patients should be lower.

Key words: aged|uremia|renal transplantation