首都医科大学学报 ›› 2004, Vol. 25 ›› Issue (1): 103-105.

• 论著·临床研究 • 上一篇    下一篇

帕金森病临床诊断现状分析

马凯, 李勇杰   

  1. 首都医科大学宣武医院功能神经外科 北京市功能神经外科研究所
  • 收稿日期:2003-04-27 修回日期:1900-01-01 出版日期:2004-01-15 发布日期:2004-01-15

Diagnosis of Parkinson Disease

Ma Kai, Li Yongjie Department of Functional Neurosurgery, Xuanwu   

  1. Hospital, Affiliate of CapitalUniversity of Medical Sciences, Beijing Institute of Functionary Neurosurgery
  • Received:2003-04-27 Revised:1900-01-01 Online:2004-01-15 Published:2004-01-15

摘要: 对944例门诊帕金森病(Parkinson disease,PD)患者的既往诊断情况进行调查,分析误诊原因。944例患者在病后<0.5年确诊者占35.1%,在病后0.5~<1.0年内确诊者为26.3%,在病后1.0~<2.0年内确诊者为17.6%,在病后2.0~<3.0年内确诊者为8.5%,在患病≥3.0年后确诊者为12.5%。发病年龄<40岁的患者规定为早发型帕金森病(young-onset Parkinson disease,YOPD),发病年龄≥40岁者规定为普通型PD。震颤型患者中YOPD确诊时间为(1.7±1.9)年,普通型PD确诊时间为(1.4±1.7)年,两者比较无明显差异。僵直型患者中YOPD确诊时间为(2.6±2.4)年,普通型PD为(1.6±1.8)年,两者比较有显著性差异(P<0.05)。提示:僵直型患者中YOPD确诊时间较普通型PD晚.

关键词: 帕金森病, 临床类型, 诊断, 误诊

Abstract: Altogether 944 cases of Parkinson disease patients were investigated about their experien ce of treatment, and the reasons of misdiagnosis were summed up. Of the 944 cases, 35.1% of them wer e diagnosed within half a year, 26.3% patients were diagnosed between 0.5 to 1 year, 17.6% patients were diagnosed between 1.0 to 2.0 year, 8.5% patients were diagnosed between 2.0 to 3.0 year, while 12.5% patients were diagnosed after 3 years. Some patients were thought to be young-onset Parkinson disease (YOPD) if the illness onset before 40 year old, while other patients were thought to be re gular PD if the illness onset after 40 year old. In the tremor patients, the diagnosis time of YOPD was (1.7± 1.9) years, while the regular one was (1.4 ±1.7) years, the difference was not significant; In the rigidity type patients, the diagnosis time of YOPD was (2.6±2.4) years, while the regular PD was (1.6 ± 1.8) years, the difference was significant. The former's time of diagnosis i s longer than the later's.

Key words: Parkinson disease, clinical type, diagnosis, misdiagnosis

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