关键词: 米索前列醇, 利多卡因, 镇痛, 社区医院

Abstract:

Objective To investigate the analgesic effect of misoprostol plus lidocaine injection cervical local anesthesia in induced abortion. Methods A retrospective analysis was used. A hundred and eight-four patients with 6~10 week gestation, during January 2010 to June 2012, were enrolled into two groups. The combined group, 92 patients, was given 400 μg misoprostol orally for one hour preoperative, followed by lidocaine cervical injection intraoperative. The control group, 92 patients, was used traditional abortion method. The difference of postoperative analgesic effect, operative time, amount of bleeding and Incidence Abortion Syndrome between the two groups were observed. Results The total analgesic effective rate of the combined group and the control group were 92.4% and 33.7%, respectively. The difference was statistically significant between the two groups(P<0.05). The incidence rate of Incidence Abortion Syndrome was higher significantly in combined group compared with that in the control group(P<0.01); however, the operation time and the amount of bleeding had no significant difference between the two groups, respectively(P>0.05). Conclusion The method of cervical misoprostol combined with lidocaine injection for abortion analgesic had significant effect. It might be suitable for Community Hospitals without special monitoring equipments.

Key words: misoprostol, lidocaine, analgesic, community hospitals