MRI诊断评估HIV相关认知功能障碍的研究进展

doi:10.3969/j.issn.1006-7795.2016.04.013

摘要/Abstract

摘要： 人类免疫缺陷病毒（human immunodeficiency virus，HIV）可以通过血-脑脊液屏障进入脑组织，引起中枢神经系统（central nervous system，CNS）紊乱，导致神经系统失调，即HIV相关认知功能障碍（HIV-associated neurocognitive disorders，HAND）。传统诊断HAND主要通过详细的神经心理认知测试及临床随访，早期发现的能力有限。磁共振技术（magnetic resonance imaging，MRI），因其较高的软组织分辨率及多种成像技术，是中枢神经系统的重要检测方法。相关研究表明，MRI相关技术有助于HAND的早期发现。因此，本文就MRI相关HAND的研究进行综述。

关键词: 人类免疫缺陷病毒, 磁共振技术, HIV相关认知功能障碍, 认知障碍

Abstract: Human immunodeficiency virus (HIV) can infect the brain tissue through the blood brain barrier, causing central nervous system (CNS) disorders, resulting neurocognitive disorders, that is the HIV-associated neurocognitive disorders (HAND). The traditional diagnosis of HAND is though the detailed the neuropsychological test and clinical follow up, however the sensitivity of it is not enough. The magnetic resonance imaging (MRI) is the major the method of detect the abnormality of the CNS, by the high resolution and multiple imaging technique. Related studies showing, MRI related technique contribute to to early detection of neurocognitive disorder, therefore, this article review the current studies.

Key words: human immunodeficiency virus, magnetic resonance imaging, HIV-associated neurocognitive disorders, neurocognitive disorder

中图分类号:

詹艺, 施裕新. MRI诊断评估HIV相关认知功能障碍的研究进展[J]. 首都医科大学学报, 2016, 37(4): 481-485.

Zhan Yi, Shi Yuxin. Review for the HIV-associated neurocognitive disorders by magnetic resonance imaging[J]. Journal of Capital Medical University, 2016, 37(4): 481-485.

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