冠状动脉动脉粥样硬化性心脏病患者认知功能下降的研究进展

doi:10.3969/j.issn.1006-7795.2025.03.014

摘要/Abstract

摘要： 冠状动脉动脉粥样硬化性心脏病（coronary heart disease, CHD）在中国疾病负担很高且仍在大幅度增加。心脏与大脑存在双向联系，CHD患者认知功能过早、过快下降越来越受到研究人员的关注，但临床医疗从业者常常更关注心脏相关症状而忽略认知功能下降对CHD患者生活质量的影响。本文从CHD患者认知功能下降的表现形式、影响因素、病理机制和干预措施几个方面对CHD患者认知下降的目前研究进展进行综述，为医疗人员更深刻地认识这一问题提供参考。

关键词: 冠状动脉动脉粥样硬化性心脏病, 认知功能, 心脑联系, 病理机制, 研究进展

Abstract: Coronary heart disease (CHD) imposes a high disease burden in China and it is still increasing significantly. There is a two-way connection between the heart and the brain, and the premature and rapid decline of cognitive function in patients with CHD has attracted increasing interesting from researchers, but clinical professionals often pay more attention to heart-related symptoms and ignore the impact of cognitive function decline on the quality of life of patients with CHD. This article reviews the current research progresses of cognitive decline in CHD patients from the aspects of manifestation, influencing factors, pathological mechanism and intervention measures. It offers a reference for medical professionals to understand this problem more deeply.

Key words: coronary heart disease, cognitive function, heart-brain connection, pathological mechanism, research progress

中图分类号:

R749

霍碧岫, 贾竑晓, 宁艳哲. 冠状动脉动脉粥样硬化性心脏病患者认知功能下降的研究进展 [J]. 首都医科大学学报, 2025, 46(3): 496-502.

Huo Bixiu, Jia Hongxiao, , Ning Yanzhe. Research progress of cognitive function decline in patients with coronary heart disease[J]. Journal of Capital Medical University, 2025, 46(3): 496-502.

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