Journal of Capital Medical University ›› 2013, Vol. 34 ›› Issue (1): 49-52.doi: 10.3969/j.issn.1006-7795.2013.01.009

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Research progress of 18F-fluorodeoxyglucose positron-emission tomography/computed tomography in the diagnosis of pulmonary tuberculosis

HAN Xue, LI Yaming, LI Xuena   

  1. Department of Nuclear Medicine, the First Hospital of China Medical University, Shenyang 110001, China
  • Received:2012-12-18 Online:2013-02-21 Published:2013-02-25

Abstract:

Lung cancer has been one of the most common malignant tumors, becoming the main cause of death among the malignant tumors in China. There are about 600,000 people dying of lung cancer each year in China now, showing an increasing trend year by year. It is predicted that China’s annual number of lung cancer will be over one million by 2025. The prognosis of lung cancer is closely related to the clinical stages, and the five-year survival rate is from 90% to below 5% from stage 0 to Ⅳ. Therefore, early detection and early diagnosis of lung cancer has a very important significance for prolonging the life of patients with lung cancer and improving the patient’s quality of life. In China, the application of 18F-fluorodeoxyglucose (FDG) positron-emission tomography (PET)/computed tomography (CT) is increasingly widespread and growing, which is mainly used in tumor field, particularly including lung cancer, breast cancer and colorectal cancer, etc. However, the 18F-FDG is not a tumor-specific tracer and some lesions of infection or inflammation, especially tuberculosis, can also increase the glucose uptake and metabolism. The differentiation of benign and malignant lung disease is a major problem in the actual work of PET-CT examination. Solving this problem will be of a huge significance for clinical work.

Key words: tuberculosis, fluorodeoxyglucose, positron emission tomography/computed tomography(PET-CT)

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