Objective To investigate risk factors of hospital-acquired pneumonia(HAP) in patients with acute ST-segment elevated myocardial infarction(STEMI). Methods We reviewed all the STEMI with HAP cases diagnosed between August 1 st, 2008 and August 1 st, 2011. The data of these patients were collected as case group. We selected a control case that was admitted in the same unit at the same time as the case patient, but without HAP. Medical information studied included possible correlated variables. All statistical analyses were performed with SPSS version 16.0. Results Medical data of 165 HAP patients with STEMI were reviewed during the study period. There were obvious differences between the two groups about age, male sex, complicated with chronic obstructive pulmonary disease (COPD), steroids/immunosuppressive drugs intake, heart function(Killip class≥Ⅲ),restriction to bed,prior major surgery, endotracheal intubation/tracheostomy, mechanical ventilation more than 48 hours,nasogastric tubes, sedation/muscle relaxants, treatment with percutaneous coronary intervention(PCI) by univariate analyses. The hospital day was longer and mortality rate was higher in the HAP group. These variables selected by univariate analyses were further analyzed by multivariate logistic regression analyses, and elder patients(older than 75 years) (OR=3.205,95% CI:1.314-7.813),COPD(OR=8.264,95% CI:2.165-31.250), length of bed limitation(OR=2.583, 95% CI:1.793-3.713), and without PCI (OR=0.361, 95% CI:0.213-0.613)were independent risk factors for to HAP in patients with STEMI.Conclusion Elder patients(older than 75 years),COPD, length of bed limitation, and without PCI were independent risk factors for HAP in patients with STEMI.
