Computed tomographic pulmonary angiography versus single photon emission computed tomography in diagnosing of pulmonary embolism: a Meta-analysis

doi:10.3969/j.issn.1006-7795.2013.01.006

Abstract

Abstract:

Objective To perform a Meta-analysis to evaluate the overall diagnostic value of computed tomography pulmonary angiography(CTPA)and single photon emission computed tomography(SPECT)in patients with suspected pulmonary embolism. Methods A literature search in PubMed,Ovid,and CNKI (China National Knowledge Infrastructure) was performed to identify relevant English and Chinese articles from 1990 to 2012. The Meta-Disc software was used to calculate the pooled sensitivity,specificity and the corresponding 95% CI. Summary receiver operating characteristic(SROC)curves,areas under curve(AUC)and the Q* index were calculated and used to evaluate the diagnostic efficiency of the two methods. Results Totally sixteen articles met our inclusion criteria. The pooled weighted sensitivity and specificity for CTPA and SPECT scanning were 0.79/0.90 and 0.86/0.95. The AUC of SROC for the two methods were 93.72% and 97.64%,and the Q* index estimates were 0.8740 and 0.9306,respectively. Comparing the Q* index of CTPA and SPECT,there was no statistically significant difference between the two methods(P>0.05). Conclusion Both CTPA and SPECT have good diagnostic performance in the diagnosis of pulmonary embolism. There was no significant difference between the two methods.

Key words: pulmonary embolism, tomography, ventilation-perfusion scan, angiography, meta analysis

CLC Number:

R817.4

SUN Pengtao, WANG Tie, LIANG Fubing. Computed tomographic pulmonary angiography versus single photon emission computed tomography in diagnosing of pulmonary embolism: a Meta-analysis[J]. Journal of Capital Medical University, 2013, 34(1): 29-35.

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URL: https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/10.3969/j.issn.1006-7795.2013.01.006

https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/Y2013/V34/I1/29

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