An experimental study on the effects of interposed abdominal compression cardiopulmonary resuscitation in a swine model of asphyxia

doi:10.3969/j.issn.1006-7795.2013.03.023

Abstract

Abstract:

Objective To compare the hemodynamic influences of standard cardiopulmonary resuscitation (STD-CPR) and interposed abdominal compression cardiopulmonary resuscitation (IAC-CPR) in a swine model of asphyxia cardiac arrest, and evaluate the effectiveness of IAC-CPR and the recovery method of asphyxic cardiac arrest. Methods Eighteen Wuzhishan inbred mini pigs underwent asphyxia by occlusion of the tracheal intubation at the end of expiration followed by cardiopulmonary resuscitation after 8 minutes without intervention. Then the pigs were randomly divided into two groups, with 9 pigs in each group and conducted STD-CPR and IAC-CPR respectively. Heart rate (HR), aorta systolic blood pressure (SBP), diastolic blood pressure (DBP), central venous pressure (CVP), arterial oxygen saturation (SaO₂%) were recorded at the baseline, CPR and ROSC 15 minutes. The aortal mean arterial pressure (MAP) and coronary perfusion pressure (CPP) were calculated and the return of spontaneous circulation (ROSC) rate and complication after ROSC were monitored. Results There were no significant differences in MAP between two groups: (46.30±13.49)mmHg vs. (54.04±13.07)mmHg, (P>0.05). The CPP in STD-CPR group was lower than in IAC-CPR group: (20.44±19.63)mmHg vs (29.56±11.57)mmHg, (P<0.05). There were no significant differences in ROSC rate. The pigs in two groups all had chest and abdomen complications, including pulmonary hemorrhage, pulmonary infarction, rib fractures, epileptic seizure and abdominal viscera ischemic necrosis. Conclusion IAC-CPR could effectively improve the CPP, but could not improve the ROSC rate.

Key words: cardiopulmonary resuscitation, chest compression, interposed abdominal compression, coronary perfusion pressure, asphyxia, cardiac arrest

CLC Number:

R 541.7

HANG Chenchen, LI Chunsheng, WU Caijun, YANG Jun, ZHANG Yi, GUO Zhijun, YIN Qin. An experimental study on the effects of interposed abdominal compression cardiopulmonary resuscitation in a swine model of asphyxia[J]. Journal of Capital Medical University, 2013, 34(3): 441-445.

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URL: https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/10.3969/j.issn.1006-7795.2013.03.023

https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/Y2013/V34/I3/441

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