Effects of calibration in patients in awakened or sedated status on postoperative muscle relaxant monitoring value

doi:10.3969/j.issn.1006-7795.2013.05.003

Journal of Capital Medical University ›› 2013, Vol. 34 ›› Issue (5): 651-654.doi: 10.3969/j.issn.1006-7795.2013.05.003

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Effects of calibration in patients in awakened or sedated status on postoperative muscle relaxant monitoring value

YIN Cheng, XUE Jixiu, YE Xin, MA Yanhui, YAN Yanhong

Department of Anesthesiology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China

Received:2013-06-12 Online:2013-10-21 Published:2013-10-22
Contact: 薛纪秀 E-mail:xuejixiu1@163.com
Supported by:
This study was supported by Hospital Project of Beijing Obsterical and Gynecological Hospital, Capital Medical University(201108), the Project of B. Braun Medical Anesthesiology Research Fund (BBF007).

Abstract

Abstract:

Objective To observe the effects of calibration in patients in awakened or sedated status for single twitch stimulation (T₁) and train-of-four (TOF) (T₄/T₁) on postoperative T₁ and TOF value. Methods Forty patients at ASAⅠor Ⅲ level, were divided into two groups at random: The awakened group (group A) and the sedation group (group S). In the group A, calibrated T₁ and TOF in the case of patients without given any sedative, and in the sedation group, calibrated when patients were given etomidate to make BIS in 40-60. Two groups of patients were not given muscle relaxants. The maximum values of T₁ and TOF were observed while the BIS value of two groups of patients with postoperative awake returned to preoperative levels. Results The postoperative T₁ maximum value of patients in the group S was obviously higher than it in the group A(P=0.005), there was no statistically significant difference between two groups of postoperative TOF in maximum value comparison(P=0.191).Conclusion In the observation of muscle relaxant monitoring, patients in awakened status underwent the T1 and TOF calibration, which caused a small effect on postoperative T₁ value, has more clinical significance.

Key words: neuromuscular monitoring, close-loop muscle relaxant injection system, calibration, train-of-four (TOF)

CLC Number:

R246.2

YIN Cheng, XUE Jixiu, YE Xin, MA Yanhui, YAN Yanhong . Effects of calibration in patients in awakened or sedated status on postoperative muscle relaxant monitoring value[J]. Journal of Capital Medical University, 2013, 34(5): 651-654.

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Effects of calibration in patients in awakened or sedated status on postoperative muscle relaxant monitoring value

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