Attentional defects induced by chronic drug abuse

doi:10.3969/j.issn.1006-7795.2013.06.025

Abstract

Abstract:

Severe influences on cognitive function caused by chronic drug abuse, such as attention, have drawn public attention. In present review, common attentional tasks were introduced, and behavioral effects on attention, caused by chronic abuse of opioid or psychomotor stimulants, were analyzed. The majority of the studies showed the negative effects on attentional function caused by opioid or psychomotor stimulants abuse, especially for the psychomotor stimulants. As for cocaine, male abusers showed poorer attention compared with their female counterparts. Cocaine-induced impairments may be concealed for abusers during their cocaine use, but may resurface during their abstinence. MDMA and cannabis abuse will significantly impair abusers' attention; while methamphetamine abusers may recover from their attention defects to some degree after certain lengthy time of abstinence.

Key words: chronic drug abuse, attention, opioid, psychomotor stimulants

CLC Number:

LI Jingye, ZHENG Zhijun, LUO Yanlin. Attentional defects induced by chronic drug abuse[J]. Journal of Capital Medical University, 2013, 34(6): 904-909.

0
/ / Recommend

Add to citation manager EndNote|Reference Manager|ProCite|BibTeX|RefWorks

URL: https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/10.3969/j.issn.1006-7795.2013.06.025

https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/Y2013/V34/I6/904

References

[1] Devlin R J, Henry J A. Clinical review: major consequences of illicit drug consumption[J]. Crit Care, 2008, 12(1):202.
[2] Chen C Y, Lin K M. Health consequences of illegal drug use[J]. Curr Opin Psychiatry, 2009, 22(3):287-292.
[3] 李景业, 郑志军, 罗艳琳.慢性药物滥用对工作记忆的行为学影响[J].现代预防医学杂志, 2013, 40(15):2835-2839.
[4] 彭聃龄.普通心理学[M].北京:北京师范大学出版社, 2001:182.
[5] Mahoney J J 3rd, Jackson B J, Kalechstein A D, et al. Acute, low-dose methamphetamine administration improves attention/information processing speed and working memory in methamphetamine-dependent individuals displaying poorer cognitive performance at baseline[J]. Prog Neuropsychopharmacol Biol Psychiatry, 2011, 35(2):459-465.
[6] Mintzer M Z, Lanier R K, Lofwall M R, et al. Effects of repeated tramadol and morphine administration on psychomotor and cognitive performance in opioid-dependent volunteers[J]. Drug Alcohol Depend. 2010, 111(3):265-268.
[7] Prosser J, London E D, Galynker I I. Sustained attention in patients receiving and abstinent following methadone maintenance treatment for opiate dependence: Performance and neuroimaging results[J]. Drug Alcohol Depend, 2009, 104(3):228-240.
[8] Roohi N N, Hamidi F, Farahani K S. Cognitive consequences of drug abuser: comparison with abuse of stimulants and opioid with regard to attention and working memory[J]. Procedia Social and Behavioral Sciences, 2010, 5:1698-1701.
[9] Brand M, Roth-Bauer M, Driessen M, et al. Executive functions and risky decision-making in patients with opiate dependence[J]. Drug Alcohol Depend, 2008, 97(1-2):64-72.
[10] Pau C W, Lee T M, Chan S F. The impact of heroin on frontal executive functions[J]. Arch Clin Neuropsychol. 2002, 17(7):663-670.
[11] Prosser J, Cohen L J, Steinfeld M, et al. Neuropsychological functioning in opiate-dependent subjects receiving and following methadone maintenance treatment[J]. Drug Alcohol Depend, 2006, 84(3):240-247.
[12] Woicik P A, Moeller S J, Alia-Klein N, et al. The neuropsychology of cocaine addiction: recent cocaine use masks impairment[J]. Neuropsychopharmacology, 2009, 34(5):1112-1122.
[13] Gooding D C, Burroughs S, Boutros N N. Attentional deficits in cocaine-dependent patients: Converging behavioral and electrophysiological evidence[J]. Psychiatry Res, 2008, 160(2):145-154.
[14] Goldstein R Z, Leskovjan A C, Hoff A L, et al. Severity of neuropsychological impairment in cocaine and alcohol addiction: association with metabolism in the prefrontal cortex[J]. Neuropsychologia, 2004, 42(11):1447-1158.
[15] De Oliveira L G, Barroso L P, Silveira C M, et al. Neuropsychological assessment of current and past crack cocaine users[J]. Subst Use Misuse, 2009, 44(13):1941-1957.
[16] Pace-Schott E F, Morgan P T, Malison R T, et al. Cocaine users differ from normals on cognitive tasks which show poorer performance during drug abstinence[J]. Am J Drug Alcohol Abuse, 2008, 34(1):109-121.
[17] Goldstein R Z, Tomasi D, Alia-Klein N, et al. The effect of practice on a sustained attention task in cocaine abusers[J]. Neuroimage, 2007, 35(1):194-206.
[18] Rahman Q, Clarke C D. Sex differences in neurocognitive functioning among abstinent recreational cocaine users[J]. Psychopharmacology(Berl), 2005, 181(2):374-380.
[19] Abi-Saab D, Beauvais J, Mehm J, et al. The effect of alcohol on the neuropsychological functioning of recently abstinent cocaine-dependent subjects[J]. Am J Addict. 2005, 14(2):166-178.
[20] Barrós-Loscertales A, Bustamante J C, Campos N V, et al. Lower activation in the right frontoparietal network during a counting Stroop task in a cocaine-dependent group[J]. Psychiatry Res, 2011, 194(2):111-118.
[21] Bada H S, Bann C M, Whitaker T M, et al. Protective factors can mitigate behavior problems after prenatal cocaine and other drug exposures[J]. Pediatrics, 2012, 130(6):e1479-e1488.
[22] Accornero V H, Amado A J, Morrow C E, et al. Impact of prenatal cocaine exposure on attention and response inhibition as assessed by continuous performance tests[J]. J Dev Behav Pediatr, 2007, 28(3):195-205.
[23] Carmody D P, Bennett D S, Lewis M. The effects of prenatal cocaine exposure and gender on inhibitory control and attention[J]. Neurotoxicol Teratol, 2011, 33(1):61-68.
[24] Kalechstein A D, Mahoney J J, Yoon J H, et al. Modafinil, but not escitalopram, improves working memory and sustained attention in long-term, high-dose cocaine users[J]. Neuropharmacology, 2013, 64:472-478.
[25] Indlekofer F, Piechatzek M, Daamen M, et al. Reduced memory and attention performance in a population-based sample of young adults with a moderate lifetime use of cannabis, ecstasy and alcohol[J]. J Psychopharmacol, 2009, 23(5):495-509.
[26] McCardle K, Luebbers S, Carter J D, et al. Chronic MDMA(ecstasy) use, cognition and mood[J]. Psychopharmacology(Berl), 2004, 173(3-4):434-439.
[27] Piechatzek M, Indlekofer F, Daamen M, et al. Is moderate substance use associated with altered executive functioning in a population-based sample of young adults[J]. Hum Psychopharmacol, 2009, 24(8):650-665.
[28] Jager G, de Win M M, van der Tweel I, et al. Assessment of cognitive brain function in ecstasy users and contributions of other drugs of abuse results from an FMRI study[J]. Neuropsychopharmacology, 2008, 33(2):247-258.
[29] Schilt T, de Win M M, Jager G, et al. Specific effects of ecstasy and other illicit drugs on cognition in poly-substance users[J]. Psychol Med, 2008, 38(9):1309-1317.
[30] McCann U D, Kuwabara H, Kumar A, et al. Persistent cognitive and dopamine transporter deficits in abstinent methamphetamine users[J]. Synapse, 2008, 62(2):91-100.
[31] Salo R, Leamon M H, Natsuaki Y, et al. Findings of preserved implicit attention in methamphetamine dependent subjects[J]. Prog Neuropsychopharmacol Biol Psychiatry, 2008, 32(1):217-223.
[32] Simon S L, Dean A C, Cordova X, et al. Methamphetamine Dependence and Neuropsychological Functioning: Evaluating Change During Early Abstinence[J]. J Stud Alcohol Drugs, 2010, 71(3):335-344.
[33] Salo R, Nordahl T E, Galloway G P, et al. Drug abstinence and cognitive control in methamphetamine-dependent individuals.J Subst Abuse Treat[J]. J Subst Abuse Treat, 2009, 37(3):292-297.
[34] Salo R, Gabay S, Fassbender C, et al. Distributed attentional deficits in chronic methamphetamine abusers: Evidence from the Attentional Network Task(ANT)[J]. Brain Cogn, 2011, 77(3):446-452.
[35] LaGasse L L, Derauf C, Smith L M, et al. Prenatal methamphetamine exposure and childhood behavior problems at 3 and 5 years of age[J]. Pediatrics, 2012, 129(4):681-688.
[36] de Sola Lopis S, Miguelez-Pan M, Pea-Casanova J, et al. Cognitive performance in recreational ecstasy polydrug users: a two-year follow-up study[J]. J Psychopharmacol, 2008, 22(5):498-510.
[37] Böcker K B, Gerritsen J, Hunault C C, et al. Cannabis with high Δ9-THC contents affects perception and visual selective attention acutely: An event-related potential study[J]. Pharmacol Biochem Behav, 2010, 96(1):67-74.
[38] Kempel P, Lampe K, Parnefjord R, et al. Auditory-evoked potentials and selective attention: different ways of information processing in cannabis users and controls[J]. Neuropsychobiology, 2003, 48(2):95-101.
[39] Abdullaev Y, Posner M I, Nunnally R, et al. Functional MRI evidence for inefficient attentional control in adolescent chronic cannabis abuse[J]. Behav Brain Res, 2010, 215(1):45-57.
[40] Medina K L, Hanson K L, Schweinsburg A D, et al. Neuropsychological functioning in adolescent marijuana users: subtle deficits detectable after a month of abstinence[J]. J Int Neuropsychol Soc, 2007, 13(5):807-820.
[41] Indlekofer F, Piechatzek M, Daamen M, et al. Reduced memory and attention performance in a population-based sample of young adults with a moderate lifetime use of cannabis, ecstasy and alcohol[J]. J Psychopharmacol, 2009, 23(5):495-509.
[42] Kedzior K K, Martin-Iverson M T. Attention-dependent reduction in prepulse inhibition of the startle reflex in cannabis users and schizophrenia patients-a pilot study[J]. Eur J Pharmacol, 2007, 560(2-3):176-182.
[43] EI Marroun H, Hudziak J J, Tiemeier H, et al. Intrauterine cannabis exposure leads to more aggressive behavior and attention problems in 18-month-old girls[J]. Drug Alcohol Depend, 2011, 118(2-3):470-474.