Abstract:

Objective With the development of lung transplantation, the relationship between cold ischemia time and bronchial anastomotic stenosis requires further study. This study aimed to improve the prognosis of patients who received lung transplantation by studying the effect of cold ischemia time on bronchial anastomotic stenosis. Methods We respectively analyzed medical records of the patients, having received lung transplantation from 2009 to 2012, including the surgical records and the reports bronchoscope. Results The incidence of bronchial anastomotic stenosis of the group, of which cold ischemia time was less than 6 hours, was higher than the group of which cold ischemia time was longer than 6 hours. Conclusion The results suggest that control of lung cold ischemia time can effectively prevent the occurrence of bronchial anastomotic stenosis after lung transplantation and improve survival of patients.

Key words: lung transplantation, cold ischemic time, bronchial anastomotic stenosis, ischemia reperfusion injury