Journal of Capital Medical University ›› 2013, Vol. 34 ›› Issue (5): 710-714.doi: 10.3969/j.issn.1006-7795.2013.05.015

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Effect of different sampling ways and different hematology analyzer on hematological parameters in SPF wistar rat

HE Peiheng, HU Zijing, JIANG Xueyun, TIAN Mi, GAO Lifang   

  1. Center for Food and Drug Safety Evaluation, Capital Medical University, Beijing 100069, China
  • Received:2012-11-22 Online:2013-10-21 Published:2013-10-22

Abstract:

Objective To summarize the effects of different blood collection methods and hematology analyzers on hematology results. Methods Eight-week old SFP Wistar rats were used in this study and results were analyzed by SPSS. Results ①The white blood cell (WBC) and platelet (PLT) results in Wistar rat blood sample by angular vein approach and abdominal aortic approach showed significant difference (P<0.05); ②The abdominal aortic approach and abdominal venous approach gave analogical results in all parameters (P>0.05); ③ADVIA 2120 and XE-2100 gave different PLT values (P<0.05)Conclusion Different blood collection ways and analyzers have effect on hematology evaluation, especially in WBC and PLT count.

Key words: wistar rat, hematological parameters, sampling ways, hematology analyzer

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