Mechanism of periprostatic adipose tissue affecting the development of prostate cancer

doi:10.3969/j.issn.1006-7795.2023.03.015

Abstract

Abstract: Periprostatic adipose tissue (PPAT), the special fat tissue surrounding the prostate gland, has unique characteristics in biological processes such as metabolism and inflammation. PPAT is closely related to the development and progression of prostate cancer. Imaging features of PPAT including PPAT thickness and volume may provide reference for the diagnosis and prognostic evaluation of prostate cancer. There are active interactions between PPAT and prostate cancer cells, which may influence prostate cancer development by several molecular pathways. The research on PPAT promotes our knowledge in the occurrence mechanism of prostate cancer, which is helpful to find new therapeutic approaches.

Key words: adipose tissue, prostate cancer, imaging, metabolism, inflammation

CLC Number:

R737.25

Xiong Tianyu, Niu Yinong. Mechanism of periprostatic adipose tissue affecting the development of prostate cancer[J]. Journal of Capital Medical University, 2023, 44(3): 457-462.

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