首都医科大学学报 ›› 1997, Vol. 18 ›› Issue (1): 48-51.

• 论著 • 上一篇    下一篇

上消化道疾病患者胃粘膜、胃液及血浆cGMP浓度测定

张益成1, 王迪2, 何绮娜3   

  1. 1. 首都医科大学附属北京安贞医院内科;2. 机械工业部设计总院医务室;3. 白求恩国际和平医院内二科
  • 收稿日期:1996-04-29 修回日期:1900-01-01 出版日期:1997-01-15 发布日期:1997-01-15

The cGMP Level of Gastric Mucosa, Gastric Juice and Plasma in Patients with Upper Alimentary Diseases

Zhang Yicheng1, Wang Di2, He Yina3   

  1. 1. Anzhen Hospital, Affiliate of Capital University of Medical Scinces;2. Clinic Design Research General Institute, Machinary Building Ministry;3. Department of Internal Medicine, Bethune International Peace Hospital
  • Received:1996-04-29 Revised:1900-01-01 Online:1997-01-15 Published:1997-01-15

摘要: 采用以碘琥珀酸环磷酸鸟苷酪氨酸甲酯(125IScGMP-TME)为标记物的环磷酸鸟苷(cGMP)放免测定法,对健康和消化道疾病患者的胃粘膜、胃液及血浆cGMP的浓度进行测定。结果上消化道肿瘤患者的胃粘膜、血浆cGMP明显高于正常值,提示cGMP对癌症的诊断、治疗监护或预后判断具有一定的意义。

关键词: 胃粘膜, 胃液, 血浆, cGMP

Abstract: The cGMP level of gastric mucosa,gastric juice and plasma in the healthy adults as well as in patients with upper alimentary diseases were assessed by RIA .The results showed that the cGMP level in gastric mucosa and plasma of patients with gastric carcinoma, gastric ulcer were significantly higher than in normal subjects( P <0.01), but in gastric juice no difference could be detected.

Key words: gastric mucosa, gacrtic fluid, plasma, cGMP

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