首都医科大学学报 ›› 1999, Vol. 20 ›› Issue (1): 24-27.

• 论著 • 上一篇    下一篇

急性出血坏死性胰腺炎的形态学观察及发病机制探讨

陈瑞芬1, 宋爱利1, 刘国贞1, 曹文军1, 袁标2, 陈佛来2   

  1. 1. 首都医科大学病理学教研室;2. 首都医科大学附属北京同仁医院外科
  • 收稿日期:1998-03-15 修回日期:1900-01-01 出版日期:1999-01-15 发布日期:2013-10-16

Morphologic Observation and Pathogenesis Discussion on Acute Haemorrhagic Necrotic Pancreatitis

Chen Ruifen1, Song Aili1, Liu Guozhen1, Cao Wenjun1, Yuan Biao2, Chen Fulai2   

  1. 1. Department of Pathology, Capital University of Medical Sciences;2. Department of Surgery, Beijing Tongren Hospital, Affiliate of Capital University of Medical Sciences
  • Received:1998-03-15 Revised:1900-01-01 Online:1999-01-15 Published:2013-10-16

摘要:

为探讨急性出血坏死性胰腺炎的发病机制,测定了胰腺炎动物模型组、正常对照组和黄腐酸钠治疗组3组大鼠的胰尾部微循环,并进行病理形态学的观察。发现:黄腐酸钠对急性出血坏死性胰腺炎有明显疗效。结果提示:胰腺微循环障碍在胰腺炎的发病中占有重要地位,为临床治疗提供了理论基础。

关键词: 胰腺炎, 微循环, 黄腐酸钠, 病理变化

Abstract:

The rats were divided into three groups: Normal control group, acute pancreatitis model group and treated group by sodium fulvate(SF). In pancreas tail microcirculation was measured and pathologic sections were examined. It was found that SFhad beneficial effects on acute haemorrhagic necrotic pancreatitis. The results indicated that microcirculatory impairment may play an important role in pancreatitis pathogenesis. The theoretical basis was provided for clinical treatment.

Key words: pancreatitis, microcirculation, sodium fulvate, pathologic change

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