叶酸治疗高半胱氨酸血症30例临床观察

首都医科大学学报 ›› 2001, Vol. 22 ›› Issue (1): 48-49.

叶酸治疗高半胱氨酸血症30例临床观察

徐晓薇¹, 杜凤和¹, 张春玲²

1. 首都医科大学附属北京天坛医院心内科;2. 阜外医院

收稿日期:2000-01-05 修回日期:1900-01-01 出版日期:2001-01-15 发布日期:2001-01-15

Clinical Observation of Folic Acid to Homocysteine Disease

Xu Xiaowei¹, Du Fenghe¹, Zhang Chunling ²

1. Department of Cardiology, Beijing Tiantan Hospital, Affiliate of Capital University of Medical Sciences;2. Fuwai Hospital

Received:2000-01-05 Revised:1900-01-01 Online:2001-01-15 Published:2001-01-15

摘要/Abstract

摘要： 为观察叶酸治疗同型半胱氨酸血症的效果及不良反应,选择冠心病中高同型半胱氨酸血症患者30例,采用自身前后对照方法,每日服叶酸0.8mg.结果:服药2周后有53.3%(16/30)的病人同型半胱氨酸浓度降至正常,4周时93.3%(28/30)的病人降至正常,用药过程中无不良反应.结果提示:口服叶酸能有效降低同型半胱氨酸浓度.

关键词: 叶酸, 冠心病, 血浆同型半胱氨酸

Abstract: To observe the effects and side-effects of folic acid to plasma homocysteine disease, 30 coronary patients with high plasma homocysteine were selected. They took 0.8 mg folic acid per day and their homocysteine levels were compared before and after being treated. The homocysteine levels of 53.3 % patients decreased to normal by taking folic acid for two weeks. The homocysteine levels of 93.3 % patients decreased to normal by taking folic acid for four weeks. No side effect was found.Conclusion: The homocysteine levels can be effectively decreased by taking folic acid for four weeks.

Key words: folic acid, coronary disease, plasma homocysteine

中图分类号:

徐晓薇;杜凤和;张春玲. 叶酸治疗高半胱氨酸血症30例临床观察[J]. 首都医科大学学报, 2001, 22(1): 48-49.

Xu Xiaowei;Du Fenghe;Zhang Chunling . Clinical Observation of Folic Acid to Homocysteine Disease[J]. Journal of Capital Medical University, 2001, 22(1): 48-49.

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