关键词: 艾滋病(AIDS), 结核, 诊断, 药物疗法

Abstract: Objective To explore the clinical characteristics,diagnosis and treatment of acquired immunodeficiency syndrome(AIDS) patients complicated with tuberculosis.Methods 55 cases suffered from AIDS complicated with tuberculosis from 1995 to 2005 were analyzed.Results The most common manifestations were fever(55 cases,100%),cough(34 cases,61.8%),night sweat(29 cases,52.7%),weight loss(28,50.9%),dyspnea(13,23.6%),chest pain(11,20%).Main clinical types of tuberculosis were tuberculous pleuritis(3 cases),lung tuberculosis(8 cases),lymphadenopathy(12 cases),25 case of disseminated tuberculosis and 7 cases of other type tuberculosis.Radiographic features: focal exudation changes in median and lower lobes,adenopathyly,pleuritis,miliary pattern or nodules.Laboratory test:CD⁺₄ T cell counts were between 0.002×10⁹～0.164×10⁹/L,Mean(0.049±0.043)×10⁹/L.In the group of 23 without anti-tuberculosis combined with high active antiretrovirus therapy therapy.12 patients died from tuberculosis 2 years later.On the contrary,5 patients died from tuberculosis among 27 cases treated with anti-tuberculosis therapy combined with high active antiretrovirus therapy.Conclusion AIDS patients complicated with tuberculosis have more disseminated tuberculosis.Their clinical manifestations and imagings are diversified,complex and difficult to diagnose.It can short course of the disease and improve prognosis of AIDS patients complicated with tuberculosis while being treated with anti-tuberculosis therapy and combined with highly active antiretrovira therapy in time.

Key words: acquired immunodeficiency syndrome, tuberculosis, diagnosis, drug therapy