低氧与缺血适应防治缺血性脑卒中新技术体系的创研及推广应用——2020年度国家科学技术进步奖二等奖

doi:10.3969/j.issn.1006-7795.2022.01.001

摘要/Abstract

摘要： 脑卒中是我国成人死亡和残疾的第一位病因,具有高发病率、高复发率、高致残率、高病死率和高经济负担的特点。吉训明教授团队致力于探索适合我国人群的脑卒中防治手段,提出“低氧组织适应”学说,发现并证实低氧适应的脑保护作用,并阐明其抗缺血缺氧损伤的机制;建立了“肢体远隔缺血适应”新方法,制定远隔缺血适应防治脑血管病的国际指南和中国专家共识等,提高了缺血性脑卒中的防治效果。

关键词: 脑血管病, 缺血性脑卒中, 低氧适应, 远隔缺血适应, 预防

Abstract: Stroke is the first cause of death and disability in China, with high morbidity, recurrence, disability, mortality, and economic burden. Professor Ji Xunming et al. devoted themselves to exploring the prevention and treatment for stroke that would be suitable for Chinese population. They proposed theory of “hypoxic tissue conditioning” and verified the brain protection effect of hypoxic conditioning and elucidated the mechanism of its anti-ischemia and hypoxic injury. A new method of “limb remote ischemic adaptation” has been established to improve the efficacy of the prevention and treatment for ischemic stroke. The international guidelines and Chinese expert consensus on remote ischemic conditioning for the prevention and treatment of cerebrovascular diseases have been formulated and achieved.

Key words: cerebrovascular disease, ischemic stroke, hypoxic conditioning, remote ischemic conditioning, prevention

中图分类号:

R743.3

赵文博, 任长虹, 李思颉, 马红蕊, 吉训明. 低氧与缺血适应防治缺血性脑卒中新技术体系的创研及推广应用——2020年度国家科学技术进步奖二等奖[J]. 首都医科大学学报, 2022, 43(1): 1-5.

Zhao Wenbo, Ren Changhong, Li Sijie, Ma Hongrui, Ji Xunming. Research and application of a new technical system of hypoxic and ischemic conditioning for prevention and treatment of ischemic stroke——The Second Prize of 2020 National Science and Technology Progress[J]. Journal of Capital Medical University, 2022, 43(1): 1-5.

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