首都医科大学学报 ›› 2010, Vol. 31 ›› Issue (1): 26-30.

• 眼科学基础及临床研究进展 • 上一篇    下一篇

折射型多焦点人工晶状体植入术后视觉质量评价

张春芳1,2, 王开杰2, 朱思泉2, 赵阳2, 李雪2   

  1. 1. 首都医科大学附属北京同仁医院, 北京同仁眼科中心, 北京市眼科学与视觉科学重点实验室;2. 北京良乡医院眼科
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2010-02-21 发布日期:2010-02-21
  • 通讯作者: 朱思泉

Quality of Vision in Patients with Refractive Multifocal Intraocular Lens Implantation

ZHANG Chun-fang1,2, WANG Kai-jie2, ZHU Si-quan2, ZHAO Yang2, LI Xue2   

  1. 1. Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Science Key Laboratory; 2. Department of Ophthalmology, Beijing Liangxiang Hospital
  • Received:1900-01-01 Revised:1900-01-01 Online:2010-02-21 Published:2010-02-21
  • Contact: ZHU Si-quan

摘要: 目的 评价折射型多焦点人工晶状体(multifocal intraocular lens,MIOL)植入术后的视觉质量。方法 采用前瞻性非随机对照研究。对114例老年性白内障患者行超声乳化白内障吸除联合人工晶状体植入术,分为折射型多焦点人工晶状体植入组(ReZoom组)和非球面单焦点人工晶状体植入组(Tecnis ZA9003组)各57例(57眼)。术后3个月时检查裸眼及矫正远、近视力、最佳矫正远视力下的近视力、波前像差、调制传递函数值、40、63、100 cm对比度视力和拟调节力,并比较视近脱镜率。结果 术后3个月,裸眼近视力和最佳矫正远视力下的近视力ReZoom组明显优于Tecnis ZA9003组(P<0.05),调节幅度ReZoom组大于TecnisZA9003组(P<0.05)。瞳孔直径3 mm和5 mm时,ReZoom组总高阶像差大于Tecnis ZA9003组,差异具有统计学意义;瞳孔直径3 mm时, ReZoom组彗差大于Tecnis ZA9003组,差异有统计学意义。在40、63、100 cm对比度视力得分(VAS分值)ReZoom组均高于TecnisZA9003组(P<0.05)。5、10、15、20 cpd调制传递函数值ReZoom组小于Tecnis ZA9003组(P<0.05)。ReZoom组近用脱镜率为96.49%,优于Tecnis ZA9003组(29.82%),差异有统计学意义。结论 与非球面单焦点人工晶状体比较,虽然折射型多焦点人工晶状体高阶像差稍高,但具有一定的拟调节力,可获得良好远、中、近视力,适合于迫切要求脱镜的患者。

关键词: 晶体, 人工, 多焦点, 视觉质量

Abstract: Objective To observe the visual performance of patients with ReZoom refractive multifocal intraocular lens(IOL) compared with aspheric monofocal IOL. Methods This was a prospective nonrandomized controlled study. Totally 114 consecutive senile cataract patients(114 eyes) were enrolled into this study. Fifty-seven cataract patients(57 eyes ) were implanted with ReZoom refractive multifocal IOL (ReZoom group), and another 57 cataract patients (57 eyes ) were implanted with aspheric monofocal IOL(Tecnis ZA9003 group). All the patients were assessed at 3 months postoperatively in the aberrations of crystalline, the modulation transfer function, contrast sensitivity of 10/100 percent in three sorts short distance(40, 63, 100 cm), uncorrected distanced visual acuity, uncorrected near visual acuity, bestcorrected distance visual acuity, best-corrected near visual acuity, distance corrected near visual acuity, pseudo-accommodation and the rate of offnear glasses. Results At 3 months postoperatively, both uncorrected near visual acuity and distance corrected near visual acuity were significantly better in ReZoom group than that in monofocal IOL group(P<0.05). The accommodative range was(3.29±0.33)D in ReZoom group and(1.55±0.27)D in TecnisZA9003 group(P<0.05). In 3/5 mm pupil diameter, the difference of the higher-total aberration between TecnisZA9003 group and ReZoom group was significant(P<0.05); in 3 mm pupil diameter, the difference of the coma aberration between TecnisZA9003 group and ReZoom group was significant(P<0.05). At 40, 63 cm and 100 cm, VA scores were higher in ReZoom group than that in TecnisZA9003 group(P<0.05). The rate of off-near glasses in ReZoom group was better than in the aspheric monofocal IOL group(P<0.05). The modulation transfer function at the spatial frequencies of 5, 10, 15, 20 cpd in ReZoom group were lower than that in Tecnis ZA9003 group(P<0.05). Conclusion Compared with aspheric monofocal IOL, the ReZoom refractive multifocal IOL increase the higher-order aberration, but it can provide certain pseudo-accommodation, better useful near and middle distance visual acuity than aspheric monofocal IOL, especially for the patients who want to get rid of spectacles.

Key words: lenses, intraocular, multifocal, quality of vision

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