从颅脑大手术到神经微创和修复的演变——微创神经外科奠基人和开拓者赵继宗院士

doi:10.3969/j.issn.1006-7795.2020.05.017

摘要/Abstract

摘要： 神经外科医学家赵继宗教授是我国微创神经外科的奠基人和开拓者，在脑血管病临床与基础研究方面的成就显著，承前启后推动神经外科学发展，带领中国神经外科走上国际舞台。2013年当选中国科学院院士。近年来积极引领神经外科投入人类本身的"终极疆域"脑认知科学临床转化研究。

关键词: 中国科学院院士, 神经外科学, 微创神经外科学, 脑认知科学, 脑血管病

Abstract: As a neurosurgeon, professor Zhao Jizong is a pioneer and founder in Chinese neurosurgical academy, who promotes the development of microsurgical techniques and theory and international collaboration. He was elected as an academician of Chinese Academy of Sciences in 2013 for his contributions to the establishment of minimal invasive-neurosurgery and achievements in clinical and basic research of complex cerebrovascular diseases. He constantly devotes himself in the translational research of brain network and function reconstruction in neurosurgical practice to advance neurosurgery in a new era.

Key words: academician of Chinese Academy of Sciences, neurosurgery, minimally invasive neurosurgery, brain cognitive science, cerebrovascular disease

中图分类号:

R651

韩小弟, 王明泽, 王硕. 从颅脑大手术到神经微创和修复的演变——微创神经外科奠基人和开拓者赵继宗院士[J]. 首都医科大学学报, 2020, 41(5): 810-817.

Han Xiaodi, Wang Mingze, Wang Shuo. The evolution from disastrous operation to minimal invasive surgery and brain reparation——Academician Zhao Jizong, the founder and pioneer of minimally invasive neurosurgery[J]. Journal of Capital Medical University, 2020, 41(5): 810-817.

参考文献

[1] Zhao J Z, Zhou L F, Zhou D B, et al. The status quo of neurosurgery in China[J]. Neurosurgery, 2008, 62(2):516-520; discussion 520-511.
[2] 肖新如, 王江飞, 赵继宗. 谈神经外科临床专业学位研究生的培养[J]. 首都医科大学学报(社会科学版), 2012:318-319.
[3] 于洮, 赵继宗. 神经外科脑血管病专业组规范化培训人员综合能力培养方法的研究[J]. 医学教育管理, 2016, 2(S2):75-77.
[4] Spetzler R F, Wilson C B, Weinstein P, et al. Normal perfusion pressure breakthrough theory[J]. Clin Neurosurg, 1978, 25:651-672.
[5] Zhao J Z, Wang S,Li J S,et al. Combination of intraoperative embolisation with surgical resection for treatment of giant cerebral arteriovenous malformations[J]. J Clin Neurosci,2000,7(Suppl 1):54-59.
[6] Shi G Z,Zhao J Z,Wang S,et al. Pre-and postoperative changes of regional cortical cerebral blood flow in patients with cerebral arteriovenous malformation[J]. Chin Med J,2003,116(8):1273-1276.
[7] Zhao J, Wang S, Li J, et al. Clinical characteristics and surgical results of patients with cerebral arteriovenous malformations[J]. Surg Neurol, 2005, 63(2):156-161; discussion 161.
[8] 赵继宗, 陆峥. 颅内复杂型动脉瘤的手术治疗策略[J]. 中国微侵袭神经外科杂志, 2001, 6(3):129-132.
[9] Zhao J, Wang S, Zhao Y, et al. Microneurosurgical management of carotid-ophthalmic aneurysms[J]. J Clin Neurosci, 2006, 13(3):330-333.
[10] 赵继宗, 韩利江, 王硕, 等. 白明胶酶与囊性脑动脉瘤发病关系的研究[J]. 中华医学杂志, 1999, 79(11):3-5.
[11] 齐巍, 赵继宗. 脑动脉瘤病人血浆弹性蛋白酶水平分析[J]. 中华实验外科杂志, 1999, 16(5):3-5.
[12] 曹勇, 赵继宗, 王硕, 等. 单核细胞趋化蛋白1和巨噬细胞炎性蛋白-1α在颅内动脉瘤壁内的表达[J]. 首都医科大学学报, 2002, 23(3):211-214.
[13] 赵继宗, 周定标, 周良辅, 等. 2464例高血压脑出血外科治疗多中心单盲研究[J]. 中华医学杂志, 2005,85(32):2238-2242.
[14] 王德江, 王梅, 刘克军, 等. 高血压脑出血外科治疗的成本-效果比较研究[J]. 中国医药导刊, 2006,8(2):127-130.
[15] Zhao J. Surgical Management of Hypertensive intracerebral hemorrhage in 2464 cases[C]. In:American Association of Neurological Surgeons 2006 Annual Meeting, 2006.
[16] Tang Y J, Wang S, Zhu M W, et al. Severe pathological manifestation of cerebral amyloid angiopathy correlates with poor outcome from cerebral amyloid angiopathy related intracranial hemorrhage[J]. Chin Med J (Engl), 2013, 126(4):603-608.
[17] Zhang Q, Liu Y, Zhang D, et al. RNF213 as the major susceptibility gene for Chinese patients with moyamoya disease and its clinical relevance[J]. J Neurosurg, 2017, 126(4):1106-1113.
[18] Yin H, Liu X, Zhang D, et al. A novel staging system to evaluate cerebral hypoperfusion in patients with moyamoya disease[J]. Stroke, 2018, 49(12):2837-2843.
[19] Zhao J. Effects of different surgical modalities on clinical outcome of moyamoya disease:A prospective cohort study[C]. In:Congress of Neurological Surgeon 2017 Annual Meeting, 2017.
[20] Jiang W J, Liu A F, Yu W, et al. Outcomes of Multimodality In situ Recanalization in Hybrid Operating Room (MIRHOR) for symptomatic chronic internal carotid artery occlusions[J]. J Neurointerv Surg, 2019, 11(8):825-832.
[21] Wang M Z, Qiu H C, Wang S, et al. A new technique for transvenous embolization of brain arteriovenous malformations in hybrid operation[J]. Chin Med J (Engl), 2018, 131(24):2993-2996.
[22] 赵继宗. 我国微创神经外科学发展现状及存在的问题[J]. 中华医学杂志, 2004, 84(10):5-7.
[23] 张岩, 王硕, 何文, 等. 术中多普勒超声及超声血管造影在脑动静脉畸形手术中的应用[J]. 中华医学杂志, 2008,88(35):2461-2464.
[24] 张岩, 林松, 赵继宗, 等. 神经导航结合术中超声在颅内海绵状血管畸形切除术中的应用研究[J]. 中华外科杂志, 2011,49(8):716-719.
[25] 赵继宗, 王硕, 袁葛, 等. 手术中脑血管造影在治疗脑血管疾病中的应用[J]. 中华医学杂志, 2006, 86(15):1044-1047.
[26] 王硕, 刘泠, 赵元立, 等. 动脉瘤夹闭手术中近红外光吲哚菁绿造影的评价[J]. 中华医学杂志, 2009,89(3):146-150.
[27] 张岩, 王硕, 卓彦, 等. 功能磁共振与神经导航融合定位和保护脑功能应用研究[J]. 中华医学杂志, 2008, 88(1):2-6.
[28] 赵继宗. 神经病学临床:脑科学研究转化基地[J]. 科技导报, 2016, 34(11):1.
[29] Deng X, Zhang Z, Zhang Y, et al. Comparison of 7.0-and 3.0-T MRI and MRA in ischemic-type moyamoya disease:preliminary experience[J]. J Neurosurg, 2016, 124(6):1716-1725.
[30] Deng X, Wei X, Zhang Y, et al. Impact of AVM location on language cortex right-hemisphere reorganization:A voxel-based lesion-symptom mapping study[J]. Clin Neurol Neurosurg, 2020, 189:105628.
[31] 尚金星, 王波, 赵继宗, 等. 大脑主要汉语功能区术前fMRI定位方法的研究[J]. 中华医学杂志, 2013,93(11):824-826.
[32] 于洮, 于嵩林, 邓晓峰, 等. 神经外科术前主要汉语功能区偏侧化的功能磁共振研究[J]. 中华医学杂志, 2019, 99(5):329-332.
[33] Deng X, Zhang Y, Xu L, et al. Comparison of language cortex reorganization patterns between cerebral arteriovenous malformations and gliomas:a functional MRI study[J]. J Neurosurg, 2015, 122(5):996-1003.
[34] Jiao Y, Lin F, Wu J, et al. Plasticity in language cortex and white matter tracts after resection of dominant inferior parietal lobule arteriovenous malformations:a combined fMRI and DTI study[J]. J Neurosurg, 2020:1-8.