Abstract: Objective To practice type 2 diabetes mellitus(2DM) screening in Beijing rural general population at age between 35 to 74 years and to analyze missed diagnosis and misdiagnosis of 2DM without oral glucose tolerance test(OGTT). Methods The study was conducted in the community of Nanfaxin, a rural suburb of Beijing, all of the inhabitants who were 35 to 74 years-old in the towns were included in the study. OGTT was performed in the subjects with fasting blood glucose(FBG)≥ 5.6 mmol/L. Results Prevalence rate of 2DM was 15.1%, in which newly diagnosed 2DM was 45.8%,which is significantly higher than the diabetes prevalence rate of major cities in 2002 national nutrition survey. Prevalence rate of impaired glucose regulation (IGR)(163 cases) was 4.9%. If not screening glucose homeostasis with OGTT 12.6% newly diagnosed 2DM, 42% impaired fasting glucose(IFG), 25.8% impaired glucose tolerance(IGT), 41.3% IFG combined IGT would be missed from diagnosis, 36.4% of newly diagnosed 2DM would be misdiagnosed as IFG. Conclusion Prevalence of 2DM in China is in a rising phase, especially in the outskirts of large cities. It is necessary to test glucose homeostasis in adult residents. Using OGTT can significantly reduce the cases of missed diagnosis and misdiagnosis.

Key words: impaired glucose regulation, oral glucose tolerance test, prevalence rate