Progress in genetic study on allergic rhinitis

doi:10.3969/j.issn.1006-7795.2013.06.006

Abstract

Abstract:

Allergic rhinitis is a disease of high prevalence and has exhibited a fairly rapid upward trend all over the world. This high prevalence translates into a high cost to society. There are still some unanswered questions related to the etiology, pathogenesis and treatment of allergic rhinitis. The genetic study of allergic rhinitis is an effective way to detect novel mechanism, prevention and personalized drug therapy in allergic rhinitis individuals. The aim of this review is to elaborate on the methods and progress of the genetic study on allergic rhinitis.

Key words: allergic rhinitis, gene, genetics

CLC Number:

R765.21

ZHAO Yanming, ZHANG Luo. Progress in genetic study on allergic rhinitis[J]. Journal of Capital Medical University, 2013, 34(6): 808-813.

0
/ / Recommend

Add to citation manager EndNote|Reference Manager|ProCite|BibTeX|RefWorks

URL: https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/10.3969/j.issn.1006-7795.2013.06.006

https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/Y2013/V34/I6/808

References

[1] Zhang L, Han D, Huang D, et al. Prevalence of self-reported allergic rhinitis in eleven major cities in China[J]. Int Arch Allergy Immunol, 2009, 149(1):47-57.
[2] Law A W, Reed S D, Sundy J S, et al. Direct costs of allergic rhinitis in the United States: estimates from the 1996 Medical Expenditure Panel Survey[J]. J Allergy Clin Immunol, 2003, 111(2):296-300.
[3] Risch N, Merikangas K. The future of genetic studies of complex human diseases[J]. Science, 1996, 273(5281):1516-1517.
[4] Ober C, Hoffjan S. Asthma genetics 2006: the long and winding road to gene discovery[J]. Genes Immun, 2006, 7(2):95-100.
[5] Haagerup A, Bjerke T, Schoitz P O, et al. Allergic rhinitis a total genome-scan for susceptibility genes suggests a locus on chromosome 4q24-q27[J]. EJHG, 2001, 9(12):945-952.
[6] Yokouchi Y, Shibasaki M, Noguchi E, et al. A genome-wide linkage analysis of orchard grass-sensitive childhood seasonal allergic rhinitis in Japanese families[J]. Genes Immun, 2002, 3(1):9-13.
[7] Haagerup A, Borglum A D, Binderup H G, et al. Fine-scale mapping of type I allergy candidate loci suggests central susceptibility genes on chromosomes 3q, 4q and Xp[J]. Allergy, 2004, 59(1):88-94.
[8] Dizier M H, Bouzigon E, Guilloud-Bataille M, et al. Genome screen in the French EGEA study: detection of linked regions shared or not shared by allergic rhinitis and asthma[J]. Genes Immun, 2005, 6(2):95-102.
[9] Bu L M, Bradley M, Soderhall C, et al. Genome-wide linkage analysis of allergic rhinoconjunctivitis in a Swedish population[J]. Clin Exp Allergy, 2006, 36(2):204-210.
[10] Brasch-Andersen C, Haagerup A, Borglum A D, et al. Highly significant linkage to chromosome 3q13.31 for rhinitis and related allergic diseases[J]. J Med Genetics, 2006, 43(3):e10.
[11] Kruse L V, Nyegaard M, Christensen U, et al. A genome-wide search for linkage to allergic rhinitis in Danish sib-pair families[J]. EJHG, 2012, 20(9):965-972.
[12] Nakamura H, Higashikawa F, Nobukuni Y, et al. Genotypes and haplotypes of CCR2 and CCR3 genes in Japanese cedar pollinosis[J]. Int Arch Allergy Immunol, 2007, 142(4):329-334.
[13] Zhang J, Noguchi E, Migita O, et al. Association of a haplotype block spanning SDAD1 gene and CXC chemokine genes with allergic rhinitis[J]. J Allergy Clin Immunol, 2005, 115(3):548-554.
[14] Chae S C, Park Y R, Oh G J, et al. The suggestive association of eotaxin-2 and eotaxin-3 gene polymorphisms in Korean population with allergic rhinitis[J]. Immunogenetics, 2005, 56(10):760-764.
[15] Movahedi M, Amirzargar A A, Nasiri R, et al. Gene polymorphisms of Interleukin-4 in allergic rhinitis and its association with clinical phenotypes[J]. Am J Otolaryngol, 2013, 34(6):676-681.
[16] Yadav A, Govindasamy G K, Naidu R. Polymorphic variants of interleukin-13 R130Q, interleukin-4 T589C, interleukin-4RA I50V, and interleukin-4RA Q576R in allergic rhinitis: A pilot study[J]. Allergy Rhinol, 2012, 3(1):e35-e40.
[17] Lu M P, Chen R X, Wang M L, et al. Association study on IL4, IL13 and IL4RA polymorphisms in mite-sensitized persistent allergic rhinitis in a Chinese population[J]. PloS One, 2011, 6(11):e27363.
[18] Hussein P Y, Zahran F, Ashour Wahba A, et al. Interleukin 10 receptor alpha subunit(IL-10RA) gene polymorphism and IL-10 serum levels in Egyptian atopic patients[J]. J Invest Allergol Clin Immunol, 2010, 20(1):20-26.
[19] Crome S Q, Wang A Y, Levings M K. Translational mini-review series on Th17 cells: function and regulation of human T helper 17 cells in health and disease[J]. Clin Exp Immunol, 2010, 159(2):109-119.
[20] Afzali B, Mitchell P, Lechler R I, et al. Translational mini-review series on Th17 cells: induction of interleukin-17 production by regulatory T cells[J]. Clin Exp Immunol, 2010, 159(2):120-130.
[21] Wang M, Zhang Y, Han D, et al. Association between polymorphisms in cytokine genes IL-17A and IL-17F and development of allergic rhinitis and comorbid asthma in Chinese subjects[J]. Hum Immunol, 2012, 73(6):647-653.
[22] Kim J J, Kim H J, Lee I K, et al. Association between polymorphisms of the angiotensin-converting enzyme and angiotensinogen genes and allergic rhinitis in a Korean population[J]. Ann Otol, Rhinol Laryngol, 2004, 113(4):297-302.
[23] Lue K H, Ku M S, Li C, et al. ACE gene polymorphism might disclose why some Taiwanese children with allergic rhinitis develop asthma symptoms but others do not[J]. Pediatr Allergy Immunol, 2006, 17(7):508-513.
[24] Lin H, Lin D, Zheng C Q. Angiotensin-converting enzyme insertion/deletion polymorphism associated with allergic rhinitis susceptibility: Evidence from 1410 subjects[J]. JRAAS, 2013,
[25] Nakamura H, Miyagawa K, Ogino K, et al. High contribution contrast between the genes of eosinophil peroxidase and IL-4 receptor alpha-chain in Japanese cedar pollinosis[J]. J Allergy Clin Immunol, 2003, 112(6):1127-1131.
[26] Sanak M, Simon H U, Szczeklik A. Leukotriene C4 synthase promoter polymorphism and risk of aspirin-induced asthma[J]. Lancet, 1997, 350(9091):1599-1600.
[27] Eskandari H G, Unal M, Ozturk O G, et al. Leukotriene C4 synthase A-444C gene polymorphism in patients with allergic rhinitis[J]. Otolaryn Head Neck, 2006, 134(6):997-1000.
[28] Han D, She W, Zhang L. Association of the CD14 gene polymorphism C-159T with allergic rhinitis[J]. Am J Rhinol Allergy, 2010, 24(1):e1-e3.
[29] Zhang Y, Duan S, Wei X, et al. Association between polymorphisms in FOXP3 and EBI3 genes and the risk for development of allergic rhinitis in Chinese subjects[J]. Hum Immunol, 2012, 73(9):939-945.
[30] Distefano J K, Taverna D M. Technological issues and experimental design of gene association studies[J]. Meth Mol Biol, 2011, 700:3-16.