Sublobectomy for early stage non-small cell lung cancer

doi:10.3969/j.issn.1006-7795.2014.06.002

Abstract

Abstract:

Sublobectomy, include anatomic segmentectomy and non-anatomic wedge resection is an alternative to lobectomy for the surgical treatment of selected patients with early stage non-small cell lung cancer. Sublobar resection can reserve more pulmonary function in these patients. Emerging evidence suggests that sublobar resection may offer survival outcomes approaching that of lobectomy for lung cancer patients whose disease meets the following criteria: stage IA disease with no regional lymph node matastasis; tumor comes up to 2 cm in diameter; located in the periphery of lung; and predominantly ground-glass appearance on CT imaging. Compared with wedge resection, segmentectomy generated the best results. Nevertheless, the evidence is currently still limited, and the above criteria are met only in a minority of patients. Large randomized trials are underway to define the clinical role of sublobar resections, and results are eagerly anticipated. Until that time, lobectomy should still be regarded as the standard therapy for patients with early stage non-small cell lung cancer.

Key words: non-small cell lung cancer, early stage, sublobectomy

CLC Number:

R734.2

Chen Donghong, Zhi Xiuyi. Sublobectomy for early stage non-small cell lung cancer[J]. Journal of Capital Medical University, 2014, 35(6): 689-693.

0
/ / Recommend

Add to citation manager EndNote|Reference Manager|ProCite|BibTeX|RefWorks

URL: https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/10.3969/j.issn.1006-7795.2014.06.002

https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/Y2014/V35/I6/689

References

[1] Siegel R, Ma J, Zou Z, et al. Cancer Statistics, 2014[J]. CA Cancer J Clin, 2014,64(1):9-29.
[2] Okumura M, Goto M, Ideguchi K, et al. Factors associated with outcome of segmentectomy for non-small cell lung cancer: long-term follow-up study at a single institution in Japan[J]. Lung Cancer, 2007,58(2):231-237.
[3] Okada M, Koike T, Higashiyama M, et al. Radical sublobar resection for small-sized non-small cell lung cancer: a multicenter study[J]. J Thorac Cardiovasc Surg, 2006,l32:769-775.
[4] Koike T, Yamato Y, Yoshiya K, et al. Intentional limited pulmonary resection for peripheral T1N0M0 small-sized lung cancer[J]. J Thorac Cardiovasc Surg, 2003,125(4):924-928.
[5] Okada M, Koike T, Higashiyama M, et al. Radical sublobar resection for small-sized non-small cell lung cancer: a multicenter study[J]. J Thorac Cardiovasc Surg, 2006,132(4):769-775.
[6] Churchill E D, Belsey R. Segmental pneumonectomy in bronchiectasis: the lingula segment of the left upper lobe[J]. Ann Surg, 1939,109(4):481-499.
[7] Jensik R L, Faber L P, Milloy F J, et al. Segmental resection for lung cancer. A fifteen-year experience[J]. J Thorac Cardiovasc Surg, 1973,66(4):563-572.
[8] Ginsberg R J, Rubinstein L V. Randomized trial of lobectomy versus limited resection for T1N0 non-small cell lung cancer. Lung Cancer Study Group[J]. Ann Thorac Surg, 1995,60(3):615-623.
[9] Patel A N, Santos R S, De Hoyos A, et al. Clinical trials of peripheral stage I(T1N0M0)non-small cell lung cancer[J]. Semin Thorac Cardio-vasc Surg, 2003,15(4):421-430.
[10] Okada M. Radical sublobar resection for lung cancer[J]. Gener Thorac Cardiovasc Surg, 2008,56(4):151-157.
[11] Kirby T J, Rice T W. Video-assisted pulmonary lobectomy[J]. Semin Thorac Cardiovasc Surg, 1993,5(4):316-320.
[12] Roviaro G C, Rebuffat C, Varoli F, et al. Videoendoscopic thoracic surgery[J]. Int Surg, 1993,78(1):4-9.
[13] Schuchert M J, Pettiford B L, Keeley S, et al. Anatomic segmentectomyin the treatment of stage I non-small cell lung cancer[J]. Ann Thorac Surg, 2007,84(3):926-932.
[14] Okada M, Nishio W, Sakamoto T, et al. Effect of tumor size on prognosis in patients with non-small cell lung cancer: the role of segmentectomy as a type of lesser resection[J]. J Thorac Cardiovasc Surg, 2005,129(1):87-93.
[15] Schuchert M J, Abbas G, Awais O. Anatomic segmentectomy for the solitary pulmonary nodule and early-stage lung cancer[J]. Ann Thorac Surg, 2012,93(6):1780-1785.
[16] Keenan R J, Landreneau R J, Maley R H Jr, et al. Segmental resectionspares pulmonary function in patients with stage I non-small cell lung cancer[J]. Ann Thorac Surg, 2004,78(1):228-233.
[17] Nomori H, Mori T, Ikeda K, et al. Segmentectomy for selected cT1N0M0 non-small cell lung cancer: a prospective study at a single institute[J]. J Thorac Cardiovasc Surg, 2012,144(1):87-93.
[18] Mohiuddin K, Haneuse S, Sofer T, et al. Relationship between margin distance and local recurrence among patients undergoing wedge resection for smll(2 cm) non-small cell lung cancer[J]. J Thorac Cardiovasc Surg, 2014,147(4):1169-1177.
[19] Fernando H C, Landreneau R J, Mandrekar S J, et al. Thirty- and ninety-day outcomes after sublobar resection with and without brachytherapy for non-small cell lung cancer: results from a multicenter phase Ⅲ study[J]. J Thorac Cardiovasc Surg, 2011,142(5):1143-1151.
[20] Martin-Ucar A E, Nakas A, Pilling J E, et al. A case-matched study of anatomical segmentectomy versus lobectomy for stage I lung cancer in high-risk patients[J]. Eur J Cardiothorac Surg, 2005,27(4):675-679.
[21] El-Sherif A, Gooding W E, Santos R, et al. Outcomes of sublobar resection versus lobectomy for stage I non-small cell lung cancer: A 13-year analysis[J]. Ann Thorac Surg, 2006,82:408-415; discussion 415-416.
[22] Mery C M, Pappas A N, Bueno R, et al. Similar long-term survival of elderly patients with non-small cell lung cancer treated with lobectomy or wedge resection within the surveillance, epidemiology and end-results database[J]. Chest, 2005,128(1):237-245.
[23] Smith C B, Wisnivesky J P. Survival following segmentectomy and lobectomy for stage I non-small cell lung cancer[J]. J Clin Oncol, 2012,30(15S):7064.
[24] Altorki N K,Yip R, Hanaoka T, et al. Sublobar resection is equivalent to lobectomy for clinical stage 1A lung cancer in solid nodules[J]. J Thorac Cardiovasc Surg, 2014,147(2):754-764.
[25] Sakurai H, Dobashi Y, Mizutani E, et al. Bronchioloalveolar carcinoma of the lung 3 centimeters or less in diameter: a prognostic assessment[J]. Ann Thorac Surg, 2004,78(5):1728-1733.
[26] Yamada S, Kohno T. Video-assisted thoracic surgery for pure ground-glass opacities 2 cm or less in diameter[J]. Ann Thorac Surg, 2004,77:1911-1915.
[27] Sugi K, Kobayashi S, Sudou M, et al. Long-term prognosis of video assisted limited surgery for early lung cancer[J]. Eur J Cardiothorac Surg, 2010,37(2):456-460.
[28] Nakao M, Yoshida J, Goto K, et al. Long-term outcomes of 50 cases of limited-resection trial for pulmonary ground-glass opacity nodules[J]. J Thorac Oncol, 2012,7(10):1563-1566.
[29] D'Amico T A. Thoracoseopic segmentectomy: technical considerations and outcomes[J]. Ann Thorac Surg, 2008,85(2):716-718.
[30] Sienel W, Stremmel C, Kirschbaum A, et al. Frequency of local recurrence following segmentectomy of stage IA non-small cell lung cancer is influenecd by segment localisation and width of resection margins implications for patient selection for segmentectomy[J]. Eur J Cardiothorac Surg, 2007,31(3):522-528.
[31] Smith C B, Swanson S J, Mhango G, et al. Survival after segmentectomy and wedge resection in stage I non-small-cell lung cancer[J]. J Thorac Oncol, 2013,8(1):73-78.
[32] Yendamuri S, Sharma R, Demmy M, et al. Temporal trends in outcomes following sublobar and lobar resections for small(≤2 cm) non-small cell lung cancers a surveillance Epidemiology End Results database analysis[J]. J Surg Resear, 2013,183(1):27-32.
[33] Koike T, Koike T, Yoshiya K, et al. Risk factor analysis of locoregional recurrence after sublobarresection in patients with clinical stage IA non-small cell lung cancer[J]. J Thorac Cardiovasc Surg, 2013,146(2):372-378.
[34] Landreneau J P, Schuchert M J, Weyant R, et al. Anatomic segmentectomy and brachytherapy mesh implantation for clinical stage I non-small cell lung cancer(NSCLC)[J]. Surgery, 2014,155(2):340-346.