Abstract: Objective To investigate the clinical value by detecting hematology index in the early experimental diagnosis of deep vein thrombosis after traumatic hip arthroplasty in old and middle-aged patients. Methods Totally 150 cases of traumatic hip arthroplasty combined with deep vein thrombosis in lower limb were selected as a study group (thrombus group) while 150 cases without deep vein thrombosis in lower limb were chosen as a control group. All those patients are from Tangshan Orthopedics Hospital during January 2011 to February 2015. To conduct¹²⁵IFIB and DD detection of collected fasting venous blood by radioimmunoassay and to detect FIB, DD, AT-Ⅲ, TpP, TAT of plasma by ELISA. Results Postoperative¹²⁵IFIB and DD of plasma testing results show that 125IFIB and DD in plasma in thrombus group increased significantly, which is obviously higher than preoperative value, as it is statistically significant. (P<0.05) On the other hand, the results from ELISA show that the area under the curve of FIB, DD, TpP, TAT and AT-Ⅲ are respectively 88.1%, 86.4%, P<0.01; 67.4%, 70.0%, P<0.05 and 64.1%, P>0.05. The results of Logistic regression analysis showed that the OR values of fibrinogen and D-two were 13.294 and 7.784 respectively(P<0.05).Conclusion fibrinogen and D-dimer in plasma have certain clinical significance in the early diagnosis of deep vein thrombosis patients after hip arthroplasty.

Key words: traumatic hip arthroplasty, I fibrinogen, D-dimer(DD), deep vein thrombosis, thrombus precursor protein (TpP), thrombin antithrombin complexes (TAT), antithrombin Ⅲ(AT-Ⅲ)