Comparative analysis of heart structure and left ventricular geometric pattern in patients with different premature ventricular contractions burden

doi:10.3969/j.issn.1006-7795.2016.06.005

Abstract

Abstract: Objective To observe the influence of different premature ventricular contractions (PVCs) burden on patients' heart structure and function, and its relevance to the left ventricular geometric pattern. Methods Totally 142 patients with PVCs were retrospectively analyzed. All the patients were divided into 3 groups by the burden of PVCs:the lower burden group (<10%, n=54), the medium burden group (10%-20%, n=55), the higher burden group (>20%, n=33). The difference and correlation between the heart structure, heart function and left ventricular geometric pattern in the 3 groups were analyzed; and the Logistic regression analyses were used to find out the risk factors of left ventricular hypertrophy. Results Compared with the higher burden group, the left atrial diameter(LAD), left ventricular outflow tract(LVOT), left ventricular internal dimension at end-diastole(LVIDD), left ventricular end-diastolic volume, left ventricular myocardial(LVM) mass and left ventricular myocardial mass index(LVMI) in the lower and medium groups were decreased, the LVEF in the lower and medium groups was increased (P<0.05). The PVCs burden was positively correlated with RVOT, LVOT, LVIDD, LVEDV, SV, LVM (P<0.05,); and was negatively correlated with LVEF (P<0.05,). With the increase of PVCs burden, the ratio of left ventricle normal geometry was decreased, and the ratio of eccentric hypertrophy geometry was increased. In a binary Logistic regression analysis, age, hypertension and PVCs burden were the risk factors of left ventricular hypertrophy in patients with PVCs. Conclusion The PVCs burden was closely related to the heart structure of the patients with PVCs. With the increase of PVCs burden, the left ventricular hypertrophy was aggravated gradually, the left ventricular systolic function was decreased, and the ratio of eccentric hypertrophy geometry was increased significantly. For patients with older age, hypertension and a heavy load of PVCs burden, doctors should monitor the cardiac function on early stage, and start the clinical intervention in time.

Key words: premature ventricular contractions, contraction burden, left ventricular function, left ventricular structure

CLC Number:

R541.7

Luo Hongyu, Hua Qi, Zhu Weiwei, Hou Haixia, Liu Rongkun. Comparative analysis of heart structure and left ventricular geometric pattern in patients with different premature ventricular contractions burden[J]. Journal of Capital Medical University, 2016, 37(6): 740-745.

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URL: https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/10.3969/j.issn.1006-7795.2016.06.005

https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/Y2016/V37/I6/740

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